Erythropoietin
- Generic Name
- Erythropoietin
- Brand Names
- Procrit, Eprex, Epprex, Epoetin Alfa Hexal, Silapo, Biopoin, Abseamed, Eporatio, NeoRecormon, Epogen, Retacrit
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 11096-26-7
- Unique Ingredient Identifier
- 64FS3BFH5W
- Background
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow . Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alf...
- Indication
用于肾功能不全合并的贫血，艾滋病本身或因治疗引起的贫血，恶性肿瘤伴发的贫血及风湿性贫血等。另外，为择期手术储存自体血而反复采血的患者，同时应用本品可预防发生贫血。
- Associated Conditions
- Anemia, Blood Loss During Surgery, Anemia caused by Zidovudine
- Associated Therapies
- -
Efficacy of Ferric Carboxymaltose With or Without EPO Reducing Red-cell Transfusion Packs in Hip Fracture Perioperative Period
- Conditions
- Interventions
- First Posted Date
- 2010-07-01
- Last Posted Date
- 2015-07-28
- Target Recruit Count
- 303
- Registration Number
- NCT01154491
- Locations
- 🇪🇸
Hospital de la Vega Baja, Orihuela, Alicante, Spain
🇪🇸Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain
🇪🇸Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
The Effects of Erythropoietin on Clinical Disability and Brain Pathology in Patients With Progressive Multiple Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2010-06-15
- Last Posted Date
- 2011-08-08
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 56
- Registration Number
- NCT01144117
- Locations
- 🇩🇰
Karen Schreiber, Copenhagen, Oesterbro, Denmark
A Safety Study of Pentoxifylline for the Treatment of Anemia
- Conditions
- Interventions
- First Posted Date
- 2010-04-13
- Last Posted Date
- 2012-03-28
- Lead Sponsor
- Fresenius Medical Care North America
- Target Recruit Count
- 48
- Registration Number
- NCT01102218
- Locations
- 🇺🇸
Fresenius Medical Care North America, Tyler, Texas, United States
Bioequivalence of a Single Subcutaneous Dose of Epoetin Beta in Healthy Japanese and Caucasian Male Subjects
- First Posted Date
- 2010-03-12
- Last Posted Date
- 2010-03-12
- Lead Sponsor
- InCROM Europe Clinical Research
- Target Recruit Count
- 23
- Registration Number
- NCT01085552
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
- First Posted Date
- 2010-01-14
- Last Posted Date
- 2015-09-29
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 152
- Registration Number
- NCT01049711
- Locations
- 🇹🇭
Siriraj Hospital, Bangkok, Thailand
Boceprevir/Peginterferon/Ribavirin for Chronic Hepatitis C: Erythropoietin Use Versus Ribavirin Dose Reduction for Anemia (P06086 AM2)
- Conditions
- Interventions
- First Posted Date
- 2009-12-01
- Last Posted Date
- 2021-02-08
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 687
- Registration Number
- NCT01023035
Azacitidine Combined to Epoetin Beta in International Prognostic Scoring System (IPSS) Low-risk and Intermediate-1 Myelodysplastic Syndrome (MDS) Patients, Resistant to Erythropoetin-stimulating Agents (ESA)
- First Posted Date
- 2009-11-18
- Last Posted Date
- 2014-03-19
- Lead Sponsor
- Groupe Francophone des Myelodysplasies
- Target Recruit Count
- 98
- Registration Number
- NCT01015352
- Locations
- 🇫🇷
Hôpital Brabois, Nancy, France
🇫🇷Hôpital Avignon, Avignon, France
🇫🇷Hôpital Archet1, Nice, France
Blood Management in Orthopedic Surgery
- First Posted Date
- 2009-10-20
- Last Posted Date
- 2009-10-20
- Lead Sponsor
- Sanquin Research & Blood Bank Divisions
- Target Recruit Count
- 2598
- Registration Number
- NCT00998088
- Locations
- 🇳🇱
Slotervaart Hospital, Amsterdam, Noord-Holland, Netherlands
🇳🇱Groene Hart Hospital, Gouda, Zuid Holland, Netherlands
🇳🇱LUMC, Leiden, Zuid-Holland, Netherlands
Effects of Erythropoietin on Depressive Symptoms and Neurocognitive Deficits in Depression and Bipolar Disorder
- First Posted Date
- 2009-06-09
- Last Posted Date
- 2012-11-09
- Lead Sponsor
- Lars Vedel Kessing, professor, MD, DMSc.
- Target Recruit Count
- 83
- Registration Number
- NCT00916552
- Locations
- 🇩🇰
Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Insulin Resistance and Substrate Metabolism After Acute Erythropoietin (EPO) Administration
- Conditions
- Interventions
- First Posted Date
- 2008-11-19
- Last Posted Date
- 2009-05-29
- Lead Sponsor
- Aarhus University Hospital
- Target Recruit Count
- 10
- Registration Number
- NCT00793767
- Locations
- 🇩🇰
Medicinsk forsknings laboratorium, Århus C, Denmark
Drug Development Updates
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