Cytisine
- Generic Name
- Cytisine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C11H14N2O
- CAS Number
- 485-35-8
- Unique Ingredient Identifier
- 53S5U404NU
- Background
Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. Also known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treat...
- Indication
Indicated for use in smoking cessation.
- Associated Conditions
- Nicotine Craving
- Associated Therapies
- -
Cytisine for Smoking Cessation
- Conditions
- Interventions
- First Posted Date
- 2023-02-15
- Last Posted Date
- 2023-04-06
- Lead Sponsor
- Centre for Addiction and Mental Health
- Target Recruit Count
- 48
- Registration Number
- NCT05729243
- Locations
- 🇨🇦
Center for Addiction and Mental Health, Toronto, Ontario, Canada
Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion)
- Conditions
- Interventions
- First Posted Date
- 2022-04-05
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- University of Auckland, New Zealand
- Target Recruit Count
- 807
- Registration Number
- NCT05311085
- Locations
- 🇳🇿
National Institute for Health Innovation, School of Population Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
PeRiopEratiVE SmokiNg CessaTion Trial
- Conditions
- Interventions
- First Posted Date
- 2021-11-01
- Last Posted Date
- 2024-10-03
- Lead Sponsor
- Population Health Research Institute
- Target Recruit Count
- 1720
- Registration Number
- NCT05102123
- Locations
- 🇨🇦
Hamilton General Hospital, Hamilton, Ontario, Canada
🇨🇦Juravinski Cancer Centre, Hamilton, Ontario, Canada
🇨🇦Kingston Health Science Centre with its research institute Kingston General Health Research Institute, Kingston, Ontario, Canada
Cytisine Compared to Combination NRT in Relapsed Smokers
- Conditions
- Interventions
- First Posted Date
- 2020-02-26
- Last Posted Date
- 2023-12-08
- Lead Sponsor
- Ottawa Heart Institute Research Corporation
- Target Recruit Count
- 13
- Registration Number
- NCT04286295
- Locations
- 🇨🇦
University of Ottawa Heart Insitute - Prevention and Wellness Centre, Ottawa, Ontario, Canada
Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
- Conditions
- Interventions
- First Posted Date
- 2019-10-15
- Last Posted Date
- 2023-11-18
- Lead Sponsor
- Loma Linda University
- Target Recruit Count
- 700
- Registration Number
- NCT04126135
- Locations
- 🇲🇳
Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
Varenicline Versus Cytisine for Smoking Cessation in Primary Care Setting
- First Posted Date
- 2019-07-11
- Last Posted Date
- 2022-11-03
- Lead Sponsor
- University of Zagreb
- Target Recruit Count
- 352
- Registration Number
- NCT04015414
- Locations
- 🇭🇷
University of Zagreb School of Medicine, Zagreb, Croatia
🇸🇮University of Ljubljana School of Medicine, Ljubljana, Slovenia
A Single Dose-escalation Study of Cytisine in Adult Smokers
- First Posted Date
- 2019-02-20
- Last Posted Date
- 2020-09-17
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 74
- Registration Number
- NCT03848208
- Locations
- 🇵🇹
BlueClinical, Porto, Portugal
Trial of Cytisine in Adult Smokers
- Conditions
- Interventions
- First Posted Date
- 2018-10-17
- Last Posted Date
- 2020-05-18
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 254
- Registration Number
- NCT03709823
- Locations
- 🇺🇸
Coastal Carolina Research Center, Inc, Mount Pleasant, South Carolina, United States
🇺🇸Clinical Research Consortium, Tempe, Arizona, United States
🇺🇸Volunteer Research Group, Knoxville, Tennessee, United States
Screening and Multiple Intervention on Lung Epidemics
- Conditions
- Interventions
- First Posted Date
- 2018-08-31
- Last Posted Date
- 2024-03-07
- Target Recruit Count
- 2000
- Registration Number
- NCT03654105
- Locations
- 🇮🇹
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2019-09-24
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 13
- Registration Number
- NCT03509948
- Locations
- 🇬🇧
Simbec Research Ltd, Cardiff, United Kingdom
Drug Development Updates
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