Cytisine

Generic Name
Cytisine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H14N2O
CAS Number
485-35-8
Unique Ingredient Identifier
53S5U404NU
Background

Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. Also known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treat...

Indication

Indicated for use in smoking cessation.

Associated Conditions
Nicotine Craving
Associated Therapies
-

A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2017-10-06
Last Posted Date
2019-10-21
Lead Sponsor
Achieve Life Sciences
Target Recruit Count
26
Registration Number
NCT03303911
Locations
🇬🇧

Simbec Research Ltd, Cardiff, United Kingdom

A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-08-31
Last Posted Date
2019-02-26
Lead Sponsor
Achieve Life Sciences
Target Recruit Count
24
Registration Number
NCT03268343
Locations
🇬🇧

Simbec Research Ltd, Merthyr Tydfil, United Kingdom

Cytisine Versus Varenicline for Smoking Cessation

First Posted Date
2016-11-08
Last Posted Date
2021-08-19
Lead Sponsor
University of Auckland, New Zealand
Target Recruit Count
679
Registration Number
NCT02957786
Locations
🇳🇿

National Institute for Health Innovation, University of Auckland, Auckland, North Island, New Zealand

Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV)

First Posted Date
2016-06-13
Last Posted Date
2020-12-17
Lead Sponsor
Boston Medical Center
Target Recruit Count
400
Registration Number
NCT02797587
Locations
🇷🇺

First St. Petersburg Pavlov State Medical University, St. Petersburg, Russian Federation

Cytisine Pharmacokinetics and Dose Response (C-DRAKS 3 and C-DRAKS 4)

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2015-10-23
Last Posted Date
2019-03-22
Lead Sponsor
University of Auckland, New Zealand
Target Recruit Count
35
Registration Number
NCT02585024
Locations
🇳🇿

Soo Hee Jeong, Auckland, New Zealand

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