Aspirin

Generic Name: Aspirin

Brand Names: Aggrenox, Alka-seltzer, Alka-seltzer Fruit Chews, Anacin, Arthriten Inflammatory Pain, Ascomp, Aspi-cor, Aspir-low, Bayer Aspirin, Bayer Womens, Bc Arthritis, Bc Original Formula, Bufferin, Duoplavin, Durlaza, Ecotrin, Ecpirin, Endodan Reformulated May 2009, Equagesic, Exaprin, Excedrin, Excedrin PM Triple Action, Fasprin, Fiorinal, Goody's Body Pain, Goody's Extra Strength, Goody's PM, Miniprin, Norgesic, Norgesic Forte, Orphengesic, Pamprin Max Formula, Robaxisal, ST. Joseph Aspirin, Stanback Headache Powder Reformulated Jan 2011, Trianal, Trianal C, Vanquish, Vazalore, Yosprala

Drug Type: Small Molecule

Chemical Formula: C_₉H_₈O_₄

CAS Number: 50-78-2

Unique Ingredient Identifier: R16CO5Y76E

Background: Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) .
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Indication: Pain, fever, and inflammation
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Associated Conditions: Acute Coronary Syndrome (ACS), Anxiety, Atherothrombotic cerebral infarction, Cardiovascular Disease (CVD), Cardiovascular Events, Cardiovascular Mortality, Colorectal Adenomas, Colorectal Cancer, Common Cold, Coronary artery reocclusion, Death, Dyspeptic signs and symptoms, Fever, Flu caused by Influenza, Headache, Heterozygous Familial Hypercholesterolemia (HeFH), Inflammation, Juvenile Idiopathic Arthritis (JIA), Major Adverse Cardiovascular and Cerebrovascular Events (MACCE), Menstrual Pain, Migraine, Morbidity, Mucocutaneous Lymph Node Syndrome, Muscle Contraction, Myalgia, Myocardial Infarction, Myocardial Infarction (MI), first occurrence, Neuropathic Pain, Pain, Pain caused by Common Cold, Pain caused by Rheumatism, Pericarditis, Polycythemia Vera (PV), Pre-Eclampsia, Rheumatism, Rheumatoid Arthritis, Rhino Sinusitis, Severe Pain, Spondyloarthropathies, Stroke, Systemic Lupus Erythematosus, Tension Headache, Thromboembolism, Thrombosis, Toothache, Transient Ischemic Attack, Vascular Death, Venous Thromboembolism, Acute Inflammation, Articular inflammation, Atherothrombotic events, Death caused by Myocardial Infarction, Fever or influenza-like illness, Moderate Pain, Recurrent Ischemic Stroke

Associated Therapies: Anti-platelet Therapy, Hemodialysis Treatment, Secondary Prevention

Clinical Trials

Pharmacodynamic-pharmacokinetic Trial, of Slow Release ASA, in the Platelet Functionalism.

Phase 1

Completed

Conditions: Cardiovascular Disease

Interventions: Drug: slow release acetyl salicylic acid
Drug: ASA
Drug: SR-ASA

First Posted Date: 2007-01-22

Last Posted Date: 2011-06-08

Lead Sponsor: Rottapharm Spain

Target Recruit Count: 50

Registration Number: NCT00425074

Locations: 🇪🇸
Hospital Universitario Virgen de la Victoria, Málaga, Spain

Study of Aspirin and TPA in Acute Ischemic Stroke

Phase 1

Withdrawn

Conditions: Acute Ischemic Stroke

First Posted Date: 2007-01-04

Last Posted Date: 2016-09-02

Lead Sponsor: Hadassah Medical Organization

Registration Number: NCT00417898

Locations: 🇮🇱
Hadassah University Medical Center, Jerusalem, Israel

Retinal Blood Flow and Microthrombi in Type 1 Diabetes

Phase 2

Completed

Conditions: Diabetic Retinopathy
Diabetes

First Posted Date: 2006-12-04

Last Posted Date: 2015-10-30

Lead Sponsor: Schepens Eye Research Institute

Target Recruit Count: 100

Registration Number: NCT00406991

Locations: 🇺🇸
Schepens Eye Research Institute, Boston, Massachusetts, United States

Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

Phase 2

Completed

Conditions: Bleeding Complication

First Posted Date: 2006-11-30

Last Posted Date: 2022-04-25

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 36

Registration Number: NCT00405613

Locations: 🇺🇸
Carolinas Medical Center, Charlotte, North Carolina, United States

A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older.

Phase 3

Completed

Conditions: Newly Diagnosed Multiple Myeloma

Interventions: Drug: Melphalan
Drug: Prednisone
Drug: Aspirin
Drug: Placebo

First Posted Date: 2006-11-30

Last Posted Date: 2017-01-11

Lead Sponsor: Celgene Corporation

Target Recruit Count: 459

Registration Number: NCT00405756

Locations: 🇦🇹
University Hospital Innsbruck, Innsbruck, Austria
🇧🇾
Republican Scientific and Practical Centre of Radiation Medicine and Human Ecology, Gomel, Belarus
🇧🇪
AZ St-Jan Brugge Oostende AV, Brugge, Belgium

and more 94 locations

Danish Aspirin Resistance Trial - Pilot Study

Not Applicable

Completed

Conditions: Drug Resistance

First Posted Date: 2006-10-18

Last Posted Date: 2007-12-12

Lead Sponsor: University of Aarhus

Target Recruit Count: 60

Registration Number: NCT00389129

Locations: 🇩🇰
Department of Cardiology, Skejby Sygehus, Aarhus University Hospital, Aarhus, Denmark

A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension

Phase 2

Terminated

Conditions: Hypertension, Pulmonary

Interventions: Drug: Simvastatin
Drug: Aspirin
Drug: Placebo

First Posted Date: 2006-10-06

Last Posted Date: 2017-07-21

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 64

Registration Number: NCT00384865

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
Tufts University School of Medicine, Boston, Massachusetts, United States
🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States

and more 1 locations