Aspirin

Generic Name: Aspirin

Brand Names: Aggrenox, Alka-seltzer, Alka-seltzer Fruit Chews, Anacin, Arthriten Inflammatory Pain, Ascomp, Aspi-cor, Aspir-low, Bayer Aspirin, Bayer Womens, Bc Arthritis, Bc Original Formula, Bufferin, Duoplavin, Durlaza, Ecotrin, Ecpirin, Endodan Reformulated May 2009, Equagesic, Exaprin, Excedrin, Excedrin PM Triple Action, Fasprin, Fiorinal, Goody's Body Pain, Goody's Extra Strength, Goody's PM, Miniprin, Norgesic, Norgesic Forte, Orphengesic, Pamprin Max Formula, Robaxisal, ST. Joseph Aspirin, Stanback Headache Powder Reformulated Jan 2011, Trianal, Trianal C, Vanquish, Vazalore, Yosprala

Drug Type: Small Molecule

Chemical Formula: C_₉H_₈O_₄

CAS Number: 50-78-2

Unique Ingredient Identifier: R16CO5Y76E

Background: Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) .
...

Indication: Pain, fever, and inflammation
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Associated Conditions: Acute Coronary Syndrome (ACS), Anxiety, Atherothrombotic cerebral infarction, Cardiovascular Disease (CVD), Cardiovascular Events, Cardiovascular Mortality, Colorectal Adenomas, Colorectal Cancer, Common Cold, Coronary artery reocclusion, Death, Dyspeptic signs and symptoms, Fever, Flu caused by Influenza, Headache, Heterozygous Familial Hypercholesterolemia (HeFH), Inflammation, Juvenile Idiopathic Arthritis (JIA), Major Adverse Cardiovascular and Cerebrovascular Events (MACCE), Menstrual Pain, Migraine, Morbidity, Mucocutaneous Lymph Node Syndrome, Muscle Contraction, Myalgia, Myocardial Infarction, Myocardial Infarction (MI), first occurrence, Neuropathic Pain, Pain, Pain caused by Common Cold, Pain caused by Rheumatism, Pericarditis, Polycythemia Vera (PV), Pre-Eclampsia, Rheumatism, Rheumatoid Arthritis, Rhino Sinusitis, Severe Pain, Spondyloarthropathies, Stroke, Systemic Lupus Erythematosus, Tension Headache, Thromboembolism, Thrombosis, Toothache, Transient Ischemic Attack, Vascular Death, Venous Thromboembolism, Acute Inflammation, Articular inflammation, Atherothrombotic events, Death caused by Myocardial Infarction, Fever or influenza-like illness, Moderate Pain, Recurrent Ischemic Stroke

Associated Therapies: Anti-platelet Therapy, Hemodialysis Treatment, Secondary Prevention

Clinical Trials

A REAl-life Study on Short-term DAPT in Patients With Ischemic Stroke or TIA

Completed

Conditions: TIA
Ischemic Stroke

Interventions: Drug: Aspirin
Drug: Clopidogrel
Drug: Ticagrelor

First Posted Date: 2022-07-27

Last Posted Date: 2024-12-05

Lead Sponsor: University of L'Aquila

Target Recruit Count: 2239

Registration Number: NCT05476081

Locations: 🇮🇹
Neurology e Stroke Unit Departement, SS Filippo e Nicola Hospital, Avezzano, Abruzzo, Italy
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Department of Neurology and Stroke Unit, Ente Ecclesiastico ospedale Generale Regionale Miulli, Acquaviva Delle Fonti, Italy
🇮🇹
Department of Neurology, Murgia Hospital Fabio Perinei SS 96, Altamura, Italy

and more 124 locations

Regorafenib With Low-dose Chemotherapies and Aspirin Followed by Standard Chemotherapies in Metastatic Colorectal Cancer

Phase 2

Recruiting

Conditions: Metastatic Colorectal Cancer

Interventions: Other: quality of life questionnaires
Procedure: Blood sample
Drug: Regorafenib
Drug: Metronomic chemotherapies
Drug: Aspirin
Drug: Bevacizumab
Drug: FOLFIRI or FOLFOX

First Posted Date: 2022-07-18

Last Posted Date: 2024-12-20

Lead Sponsor: Centre Hospitalier Universitaire de Besancon

Target Recruit Count: 446

Registration Number: NCT05462613

Locations: 🇫🇷
Hôpital Privé Jean Mermoz, Lyon, France
🇫🇷
CHU Estain, Clermont-Ferrand, France
🇫🇷
CHU Montpellier, Montpellier, France

and more 13 locations

Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Phase 4

Recruiting

Conditions: Coronary Artery Disease

Interventions: Drug: aspirin

First Posted Date: 2022-06-14

Last Posted Date: 2024-08-27

Lead Sponsor: Asan Medical Center

Target Recruit Count: 3944

Registration Number: NCT05418556

Locations: 🇰🇷
Veterans Hospital, Daegu, Korea, Republic of
🇰🇷
Dankook University Hospital, Chungnam, Korea, Republic of
🇰🇷
Chungnam National University Sejong Hospital, Chungnam, Korea, Republic of

and more 22 locations

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Phase 2

Recruiting

Conditions: T Cells
Colorectal Cancer
Lynch Syndrome

Interventions: Drug: Naproxen
Drug: Aspirin

First Posted Date: 2022-06-09

Last Posted Date: 2024-03-13

Lead Sponsor: M.D. Anderson Cancer Center

Target Recruit Count: 40

Registration Number: NCT05411718

Locations: 🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

Efficacy and Safety of Aspirin in Patients With Chronic Coronary Syndromes Without Revascularization

Phase 4

Recruiting

Conditions: Stable Angina Pectoris
Coronary Artery Disease
Ischemic Heart Disease

Interventions: Drug: Aspirin
Drug: No aspirin

First Posted Date: 2022-04-26

Last Posted Date: 2023-10-04

Lead Sponsor: Takeshi Morimoto

Target Recruit Count: 2890

Registration Number: NCT05347069

Locations: 🇯🇵
Kyoto University Hospital, Kyoto, Japan

Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat

Phase 4

Conditions: Sore Throat

Interventions: Drug: Benzydamine hydrochloride
Drug: Aspirin

First Posted Date: 2022-04-25

Last Posted Date: 2022-05-12

Lead Sponsor: Rehman Medical Institute - RMI

Target Recruit Count: 60

Registration Number: NCT05343429

Locations: 🇵🇰
Rehman Medical Institute, Peshawar, Khyber Pakhtunkhwa, Pakistan

Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction

Phase 4

Recruiting

Conditions: Branch Atheromatous Disease

Interventions: Drug: Tirofiban hydrochloride sodium chloride injection
Drug: Tirofiban hydrochloride sodium chloride injection placebo
Drug: Aspirin

First Posted Date: 2022-04-05

Last Posted Date: 2022-11-07

Lead Sponsor: Beijing Tiantan Hospital

Target Recruit Count: 970

Registration Number: NCT05310968

Locations: 🇨🇳
Mengzhou People's Hospital, Henan, Henan, China
🇨🇳
The People's Hospital of Xiuwu County, Jiaozuo, Henan, China
🇨🇳
The First People's Hospital of Nanyang, Nanyang, Henan, China

and more 17 locations

Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects

Phase 1

Completed

Conditions: Drug Drug Interaction

Interventions: Drug: DWP14012
Drug: Aspirin

First Posted Date: 2022-03-31

Last Posted Date: 2023-04-05

Lead Sponsor: Daewoong Pharmaceutical Co. LTD.

Target Recruit Count: 24

Registration Number: NCT05304845

Locations: 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of

GM03 - Platelet RNA Signatures of Aspirin

Early Phase 1

Completed

Conditions: Platelet Aggregation Inhibitors
Aspirin
Ticagrelor
RNA

Interventions: Drug: Aspirin
Drug: Ticagrelor

First Posted Date: 2022-03-14

Last Posted Date: 2022-03-14

Lead Sponsor: Duke University

Target Recruit Count: 135

Registration Number: NCT05278637

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion

Phase 4

Recruiting

Conditions: Acute Ischemic Stroke

Interventions: Drug: Tirofiban
Drug: Acetylsalicylic acid

First Posted Date: 2022-02-07

Last Posted Date: 2024-03-07

Lead Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Target Recruit Count: 240

Registration Number: NCT05225961

Locations: 🇪🇸
Virgen del Rocío Hospital, Seville, Spain
🇪🇸
Ramón y Cajal Hospital, Madrid, Spain
🇪🇸
Complejo Hospital Universitario de Badajoz, Badajoz, Spain

and more 10 locations

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