Aspirin

Generic Name: Aspirin

Brand Names: Aggrenox, Alka-seltzer, Alka-seltzer Fruit Chews, Anacin, Arthriten Inflammatory Pain, Ascomp, Aspi-cor, Aspir-low, Bayer Aspirin, Bayer Womens, Bc Arthritis, Bc Original Formula, Bufferin, Duoplavin, Durlaza, Ecotrin, Ecpirin, Endodan Reformulated May 2009, Equagesic, Exaprin, Excedrin, Excedrin PM Triple Action, Fasprin, Fiorinal, Goody's Body Pain, Goody's Extra Strength, Goody's PM, Miniprin, Norgesic, Norgesic Forte, Orphengesic, Pamprin Max Formula, Robaxisal, ST. Joseph Aspirin, Stanback Headache Powder Reformulated Jan 2011, Trianal, Trianal C, Vanquish, Vazalore, Yosprala

Drug Type: Small Molecule

Chemical Formula: C_₉H_₈O_₄

CAS Number: 50-78-2

Unique Ingredient Identifier: R16CO5Y76E

Background: Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) .
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Indication: Pain, fever, and inflammation
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Associated Conditions: Acute Coronary Syndrome (ACS), Anxiety, Atherothrombotic cerebral infarction, Cardiovascular Disease (CVD), Cardiovascular Events, Cardiovascular Mortality, Colorectal Adenomas, Colorectal Cancer, Common Cold, Coronary artery reocclusion, Death, Dyspeptic signs and symptoms, Fever, Flu caused by Influenza, Headache, Heterozygous Familial Hypercholesterolemia (HeFH), Inflammation, Juvenile Idiopathic Arthritis (JIA), Major Adverse Cardiovascular and Cerebrovascular Events (MACCE), Menstrual Pain, Migraine, Morbidity, Mucocutaneous Lymph Node Syndrome, Muscle Contraction, Myalgia, Myocardial Infarction, Myocardial Infarction (MI), first occurrence, Neuropathic Pain, Pain, Pain caused by Common Cold, Pain caused by Rheumatism, Pericarditis, Polycythemia Vera (PV), Pre-Eclampsia, Rheumatism, Rheumatoid Arthritis, Rhino Sinusitis, Severe Pain, Spondyloarthropathies, Stroke, Systemic Lupus Erythematosus, Tension Headache, Thromboembolism, Thrombosis, Toothache, Transient Ischemic Attack, Vascular Death, Venous Thromboembolism, Acute Inflammation, Articular inflammation, Atherothrombotic events, Death caused by Myocardial Infarction, Fever or influenza-like illness, Moderate Pain, Recurrent Ischemic Stroke

Associated Therapies: Anti-platelet Therapy, Hemodialysis Treatment, Secondary Prevention

Clinical Trials

Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions

Not Applicable

Active, not recruiting

Conditions: De Novo Stenosis
Coronary Artery Disease
Percutaneous Coronary Intervention

Interventions: Device: Lepu Paclitaxel coated balloon
Device: Resolute Integrity Zotarolimus eluting stents
Drug: Aspirin
Drug: Ticagrelor
Drug: Clopidogrel

First Posted Date: 2022-01-26

Last Posted Date: 2024-01-24

Lead Sponsor: Xijing Hospital

Target Recruit Count: 370

Registration Number: NCT05209412

Locations: 🇨🇳
Ling Tao, Xi'an, Shannxi, China

Aspirin for the Management of Endometriosis-associated Pelvic Pain

Phase 4

Recruiting

Conditions: Pelvic Pain

Interventions: Drug: Drospirenone ethinyl estradiol
Drug: Aspirin

First Posted Date: 2021-12-14

Last Posted Date: 2022-01-24

Lead Sponsor: Women's Hospital School Of Medicine Zhejiang University

Target Recruit Count: 220

Registration Number: NCT05156879

Locations: 🇨🇳
Women's Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, China

Continuation of Aspirin Before Isolated Heart Valve Surgery

Conditions: Isolated Heart Valve Surgery

Interventions: Drug: Aspirin

First Posted Date: 2021-12-09

Last Posted Date: 2021-12-09

Lead Sponsor: University of Liege

Target Recruit Count: 500

Registration Number: NCT05151796

Locations: 🇧🇪
CHU of Liege, Liège, Liege, Belgium

Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients

Phase 4

Recruiting

Conditions: Non ST Segment Elevation Acute Coronary Syndrome

Interventions: Drug: No aspirin
Drug: Aspirin

First Posted Date: 2021-11-18

Last Posted Date: 2023-07-19

Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Target Recruit Count: 3090

Registration Number: NCT05125276

Locations: 🇳🇱
Amsterdam UMC, location VUmc, Amsterdam, Netherlands
🇳🇱
Amsterdam UMC, location AMC, Amsterdam, Netherlands

Effects of Edoxaban on Platelet Aggregation

Phase 2

Recruiting

Conditions: SCAD
AMI

Interventions: Drug: ASA
Drug: Clopidogrel
Drug: Edoxaban

First Posted Date: 2021-11-16

Last Posted Date: 2023-06-23

Lead Sponsor: University of Sao Paulo

Target Recruit Count: 70

Registration Number: NCT05122455

Locations: 🇧🇷
Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil

A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants

Phase 2

Completed

Conditions: Coronary Artery Disease
Healthy Participants

Interventions: Drug: Ticagrelor
Drug: BMS-986141
Drug: Aspirin

First Posted Date: 2021-10-26

Last Posted Date: 2023-12-05

Lead Sponsor: Bristol-Myers Squibb

Target Recruit Count: 58

Registration Number: NCT05093790

Locations: 🇬🇧
Local Institution - 0001, Edinburgh, United Kingdom

ASPIRED-XT: ASPirin Intervention for the REDuction of Colorectal Cancer Risk -EXTension

Early Phase 1

Active, not recruiting

Conditions: Colorectal Cancer

Interventions: Drug: Aspirin
Other: Placebo

First Posted Date: 2021-09-27

Last Posted Date: 2024-12-04

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 161

Registration Number: NCT05056896

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

DAILY: Vitamin D, Aspirin, ExercIse, Low Saturated Fat Foods StudY in Colorectal Cancer Patients With Minimal Residual Disease

Not Applicable

Recruiting

Conditions: Colorectal Cancer
Colon Cancer

Interventions: Drug: Aspirin
Drug: Vitamin D
Dietary Supplement: Diet
Other: Physical Activity
Behavioral: Behavioral Support Counseling Sessions

First Posted Date: 2021-09-05

Last Posted Date: 2024-08-21

Lead Sponsor: M.D. Anderson Cancer Center

Target Recruit Count: 19

Registration Number: NCT05036109

Locations: 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States

AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation

Phase 3

Recruiting

Conditions: Aortic Stenosis

Interventions: Drug: Acetylsalicylic acid
Drug: Apixaban
Drug: Rivaroxaban
Drug: Edoxaban

First Posted Date: 2021-09-05

Last Posted Date: 2022-11-14

Lead Sponsor: Oslo University Hospital

Target Recruit Count: 360

Registration Number: NCT05035277

Locations: 🇳🇴
Haukeland University Hospital, Bergen, Norway
🇳🇴
Oslo Univesity Hospital - Ullevål, Oslo, Norway
🇳🇴
Oslo University Hospital - Rikshospitalet, Oslo, Norway

Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT)

Phase 2

Recruiting

Conditions: Bipolar Disorder

Interventions: Drug: acetylsalicylic acid
Drug: Calcium

First Posted Date: 2021-09-05

Last Posted Date: 2024-01-17

Lead Sponsor: Lars Vedel Kessing

Target Recruit Count: 250

Registration Number: NCT05035316

Locations: 🇩🇰
Psychiatric Center Copenhagen, Copenhagen, Denmark

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