Escitalopram

Generic Name
Escitalopram
Brand Names
Cipralex, Lexapro
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
128196-01-0
Unique Ingredient Identifier
4O4S742ANY
Background

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...

Indication

Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...

Associated Conditions
Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
Associated Therapies
-

Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder

Phase 3
Completed
Conditions
First Posted Date
2006-07-12
Last Posted Date
2008-12-22
Lead Sponsor
AstraZeneca
Target Recruit Count
450
Registration Number
NCT00351169
Locations
🇪🇸

Research Site, Zamora, Spain

Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)

Phase 3
Completed
Conditions
First Posted Date
2006-03-22
Last Posted Date
2006-07-26
Lead Sponsor
Abarbanel Mental Health Center
Target Recruit Count
100
Registration Number
NCT00305500
Locations
🇮🇱

Abarbanel MHC, Bat-Yam, Israel

PTSD Prevention Using Escitalopram

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2006-03-08
Last Posted Date
2013-12-31
Lead Sponsor
Sheba Medical Center
Target Recruit Count
450
Registration Number
NCT00300313
Locations
🇮🇱

Hadassa Medical Center, Jerusalem, Israel

🇮🇱

Barzilai Medical Center, Ashkelon, Israel

🇮🇱

Soroka Medical Center, Beer-Sheva, Israel

and more 2 locations

Memory Functioning and Antidepressant Treatment

Phase 3
Completed
Conditions
First Posted Date
2006-02-27
Last Posted Date
2009-02-17
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
60
Registration Number
NCT00296933
Locations
🇨🇦

University Health Network, Toronto, Ontario, Canada

Treatment of Depression Following Multiple Brain Tests

First Posted Date
2006-02-27
Last Posted Date
2012-04-27
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
28
Registration Number
NCT00296777
Locations
🇺🇸

Depression Evaluation Service - New York State Psychiatric Institute, New York, New York, United States

Mineralocorticoid Receptor in the Treatment of Severe Depression

Not Applicable
Completed
Conditions
First Posted Date
2006-02-23
Last Posted Date
2017-05-30
Lead Sponsor
Universitätsklinikum Hamburg-Eppendorf
Target Recruit Count
65
Registration Number
NCT00295347
Locations
🇩🇪

University Hospital Hamburg-Eppendorf, Hamburg, Germany

Treatment Resistant Bipolar Depression

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2006-01-04
Last Posted Date
2015-12-16
Lead Sponsor
Queen's University
Target Recruit Count
1
Registration Number
NCT00272025
Locations
🇨🇦

Providence Care, Mental Health Services, Kingston, Ontario, Canada

DBT and Escitalopram in Borderline Personality Disorder

Not Applicable
Conditions
First Posted Date
2005-11-21
Last Posted Date
2005-11-21
Lead Sponsor
Bronx VA Medical Center
Registration Number
NCT00255554
Locations
🇺🇸

Bronx VA Medical Center, Bronx, New York, United States

Functional Dyspepsia Treatment Trial

First Posted Date
2005-11-04
Last Posted Date
2014-07-25
Lead Sponsor
Mayo Clinic
Target Recruit Count
292
Registration Number
NCT00248651
Locations
🇺🇸

Northwestern University Chicago, Chicago, Illinois, United States

🇺🇸

Baylor College of Medicine, Houston, Texas, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 4 locations

MOTIV Study- Effect of Antidepressive Treatment by Escitalopram in Patients Undergoing Coronary Artery Bypass Grafting

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-10-24
Last Posted Date
2012-03-19
Lead Sponsor
Hopital Jean Minjoz
Target Recruit Count
368
Registration Number
NCT00243477
Locations
🇫🇷

Sidney Chocron, Besançon, Doubs, France

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