Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Association of Intravenous Ketamine With Thoracic Epidural Analgesia: Effects on Pain and Respiratory Function Following Thoracotomy.
- First Posted Date
- 2008-07-31
- Last Posted Date
- 2014-08-28
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Target Recruit Count
- 21
- Registration Number
- NCT00726258
- Locations
- 🇫🇷
Service de chirurgie Orthopédique-Traumatologie - Hopital Sainte Marguerite, Marseille, France
Lidocaine and Ketamine in Abdominal Surgery
- Conditions
- Interventions
- First Posted Date
- 2008-07-23
- Last Posted Date
- 2017-07-26
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 64
- Registration Number
- NCT00721110
- Locations
- 🇺🇸
Cleveland Clinic/Hillcrest Hospital, Mayfield Heights, Ohio, United States
Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-06-04
- Last Posted Date
- 2012-05-09
- Lead Sponsor
- Yale University
- Target Recruit Count
- 30
- Registration Number
- NCT00690170
- Locations
- 🇺🇸
Veterans Administration Hospital, West Haven, Connecticut, United States
Ketamine as an Anaesthetic Agent in Electroconvulsive Therapy (ECT)
- First Posted Date
- 2008-05-20
- Last Posted Date
- 2013-03-29
- Lead Sponsor
- Northside Clinic, Australia
- Target Recruit Count
- 83
- Registration Number
- NCT00680433
- Locations
- 🇦🇺
Wesley Hospital, Sydney, New South Wales, Australia
Diabetic Neuropathy Topical Treatment
- Conditions
- Interventions
- First Posted Date
- 2008-04-18
- Last Posted Date
- 2008-04-18
- Target Recruit Count
- 200
- Registration Number
- NCT00661063
- Locations
- 🇧🇷
Santa Casa de São Paulo, São Paulo, Brazil
Ketamine Frequency Treatment for Major Depressive Disorder
- Conditions
- Interventions
- First Posted Date
- 2008-03-28
- Last Posted Date
- 2011-06-06
- Lead Sponsor
- Essentia Health
- Registration Number
- NCT00646087
- Locations
- 🇺🇸
St. Mary's Duluth Clinic Health System, Duluth, Minnesota, United States
The Effect of Perioperative Ketamine on Acute and Chronic Pain After Major Back Surgery
- First Posted Date
- 2008-02-20
- Last Posted Date
- 2013-04-15
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 160
- Registration Number
- NCT00618423
- Locations
- 🇨🇭
University Hospital of Geneva, Geneva, Canton of Geneva, Switzerland
Pharmacokinetics of Low Dose Ketamine Infusion
- First Posted Date
- 2008-02-20
- Last Posted Date
- 2016-10-26
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 5
- Registration Number
- NCT00618397
- Locations
- 🇺🇸
Children's Medical Center Dallas, University of Texas Southwestern, Dallas, Texas, United States
Ketamine Compared to Propofol for Pediatric GI Endoscopy
- First Posted Date
- 2008-02-13
- Last Posted Date
- 2009-07-02
- Target Recruit Count
- 34
- Registration Number
- NCT00614159
Ketamine Pharmacokinetics in Children Having Heart Surgery
- First Posted Date
- 2008-01-21
- Last Posted Date
- 2013-02-27
- Lead Sponsor
- Arkansas Children's Hospital Research Institute
- Target Recruit Count
- 18
- Registration Number
- NCT00598195
- Locations
- 🇺🇸
Arkansas Children's Hospital, Little Rock, Arkansas, United States
Drug Development Updates
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