Overview
Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was first isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and has been polymerized for vinyl production . It it suggested that many organic fatty acids exert fungicidal or fungistatic actions. Undecylenic acid also possesses antifungal properties, but is never used on its own for antifungal purposes. Salts of undecylenate are found in topical over-the-counter or mixture products as antifungal agents. Zinc undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete’s foot and relieves itching, burning, and irritation associated with the skin condition. Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone.
Indication
Indicated for the treatment of fungal infections as a salt form. No therapeutic indications on its own.
Associated Conditions
- Ringworm
- Tinea Pedis
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
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No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
---|---|---|---|---|---|
Sansar LLC | 83691-010 | TOPICAL | 10 g in 100 g | 4/18/2025 | |
Jiangxi Hemei Pharmaceutical Co., Ltd | 84010-135 | TOPICAL | 25 g in 100 mL | 6/19/2025 | |
Shenzhen Earth Surface Trading Co., Ltd. | 85636-001 | TOPICAL | 100 mg in 1 mL | 5/27/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
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No EMA approvals found for this drug. |
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
VETIC CREAM | SIN09862P | CREAM | 10% | 7/2/1998 | |
VETIC CREAM | SIN09862P | CREAM | 5% | 7/2/1998 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
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No NMPA approvals found for this drug. |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
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No PPB approvals found for this drug. |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
---|---|---|---|---|---|
PEDOZ ANTI-FUNGAL POWDER bottle | 14840 | Medicine | A | 9/5/1991 | |
Flexitol Anti Fungal Liquid | 181616 | Medicine | A | 3/29/2011 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
---|---|---|---|---|---|
OVOQUINOL CONES | lab nadeau ltée, division of technilab inc. | 00522074 | Suppository - Vaginal | 50 MG / SUP | 12/31/1963 |
DESENEX ANTIFUNGAL POWDER | ciba self medication | 02021862 | Powder - Topical | 2 % | 12/31/1994 |
DESENEX ANTIFUNGAL POWDER | ciba self medication | 02021862 | Powder - Topical | 20 % | 12/31/1994 |
FUNGAL FOOT SPRAY 0.1% | mueller sports medicine, inc. | 00240664 | Aerosol - Topical | .1 % | 12/31/1970 |
FOOT SPRAY WITH POWDER | mueller sports medicine, inc. | 00240656 | Aerosol - Topical | .35 % | 12/31/1970 |
FUNGI-RID - LIQ 10% | tripod family foot care centres inc. | 02222736 | Liquid - Topical | 10 % | 8/30/1996 |
OVOQUINOL CRM VAGINALE | lab nadeau ltée, division of technilab inc. | 00464651 | Cream - Vaginal | 1 % | 12/31/1980 |
DESENEX MEDICATED SPRAY-ON POWDER | novartis consumer health canada inc. | 02021900 | Aerosol
,
Powder - Topical | 20 % | 12/31/1994 |
DESENEX MEDICATED SPRAY-ON POWDER | novartis consumer health canada inc. | 02021900 | Aerosol
,
Powder - Topical | 2 % | 12/31/1994 |
ZINC UNDECYLENATE | regal pharms, division of bradcan corporation | 00595926 | Powder - Topical | 20 % | 12/31/1983 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
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No CIMA AEMPS (Spain) approvals found for this drug. |
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
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No Philippines FDA approvals found for this drug. |
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Saudi SFDA approvals found for this drug. |
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Malaysia NPRA approvals found for this drug. |
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
---|---|---|---|---|---|
No UK EMC drug information found for this drug. |
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