MedPath

Undecylenic acid

Generic Name
Undecylenic acid
Brand Names
Fungi-nail, Fungi-nail Toe and Foot, Fungicure Maximum Strength, Sanafitil Antifungal, Terpenicol, Tineacide Antifungal, Ting
Drug Type
Small Molecule
Chemical Formula
C11H20O2
CAS Number
112-38-9
Unique Ingredient Identifier
K3D86KJ24N

Overview

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was first isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and has been polymerized for vinyl production . It it suggested that many organic fatty acids exert fungicidal or fungistatic actions. Undecylenic acid also possesses antifungal properties, but is never used on its own for antifungal purposes. Salts of undecylenate are found in topical over-the-counter or mixture products as antifungal agents. Zinc undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete’s foot and relieves itching, burning, and irritation associated with the skin condition. Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone.

Indication

Indicated for the treatment of fungal infections as a salt form. No therapeutic indications on its own.

Associated Conditions

  • Ringworm
  • Tinea Pedis

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor

No clinical trials found

No clinical trials found for this drug

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Sansar LLC
83691-010
TOPICAL
10 g in 100 g
4/18/2025
Jiangxi Hemei Pharmaceutical Co., Ltd
84010-135
TOPICAL
25 g in 100 mL
6/19/2025
Shenzhen Earth Surface Trading Co., Ltd.
85636-001
TOPICAL
100 mg in 1 mL
5/27/2025

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
VETIC CREAM
SIN09862P
CREAM
10%
7/2/1998
VETIC CREAM
SIN09862P
CREAM
5%
7/2/1998

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product
ARTG ID
Sponsor
Registration Type
Status
Registration Date
PEDOZ ANTI-FUNGAL POWDER bottle
14840
Medicine
A
9/5/1991
Flexitol Anti Fungal Liquid
181616
Medicine
A
3/29/2011

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
OVOQUINOL CONES
lab nadeau ltée, division of technilab inc.
00522074
Suppository - Vaginal
50 MG / SUP
12/31/1963
DESENEX ANTIFUNGAL POWDER
ciba self medication
02021862
Powder - Topical
2 %
12/31/1994
DESENEX ANTIFUNGAL POWDER
ciba self medication
02021862
Powder - Topical
20 %
12/31/1994
FUNGAL FOOT SPRAY 0.1%
mueller sports medicine, inc.
00240664
Aerosol - Topical
.1 %
12/31/1970
FOOT SPRAY WITH POWDER
mueller sports medicine, inc.
00240656
Aerosol - Topical
.35 %
12/31/1970
FUNGI-RID - LIQ 10%
tripod family foot care centres inc.
02222736
Liquid - Topical
10 %
8/30/1996
OVOQUINOL CRM VAGINALE
lab nadeau ltée, division of technilab inc.
00464651
Cream - Vaginal
1 %
12/31/1980
DESENEX MEDICATED SPRAY-ON POWDER
novartis consumer health canada inc.
02021900
Aerosol ,  Powder - Topical
20 %
12/31/1994
DESENEX MEDICATED SPRAY-ON POWDER
novartis consumer health canada inc.
02021900
Aerosol ,  Powder - Topical
2 %
12/31/1994
ZINC UNDECYLENATE
regal pharms, division of bradcan corporation
00595926
Powder - Topical
20 %
12/31/1983

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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