Lansoprazole
- Generic Name
- Lansoprazole
- Brand Names
- Prevacid, Prevpac
- Drug Type
- Small Molecule
- Chemical Formula
- C16H14F3N3O2S
- CAS Number
- 103577-45-3
- Unique Ingredient Identifier
- 0K5C5T2QPG
- Background
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other patholog...
- Indication
Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of sever...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Helicobacter Pylori Infection, Symptomatic Gastroesophageal Reflux Disease (sGERD), Ulcer Healing, Zollinger-Ellison Syndrome, Active Duodenal ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Maintenance of healing Erosive esophagitis
- Associated Therapies
- -
Lansoprazole 30 mg DR Capsule Fasting Study
- First Posted Date
- 2010-01-11
- Last Posted Date
- 2010-12-08
- Lead Sponsor
- Teva Pharmaceuticals USA
- Target Recruit Count
- 56
- Registration Number
- NCT01045967
- Locations
- 🇺🇸
PRACS Institute, Ltd., Fargo, North Dakota, United States
Lansoprazole 30 mg DR Capsule Replicate Food Study
- First Posted Date
- 2010-01-11
- Last Posted Date
- 2010-12-08
- Lead Sponsor
- Teva Pharmaceuticals USA
- Target Recruit Count
- 50
- Registration Number
- NCT01046084
- Locations
- 🇺🇸
Gateway Medical Research, Inc., St. Charles, Missouri, United States
Lansoprazole 30 mg DR Capsule Fasting Replicate Sprinkle Study
- First Posted Date
- 2010-01-11
- Last Posted Date
- 2010-12-08
- Lead Sponsor
- Teva Pharmaceuticals USA
- Target Recruit Count
- 50
- Registration Number
- NCT01046253
- Locations
- 🇺🇸
Gateway Medical Research, Inc., St. Charles, Missouri, United States
Lansoprazole for Subgroups of Functional Dyspepsia
- First Posted Date
- 2009-12-29
- Last Posted Date
- 2014-04-15
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT01040455
- Locations
- 🇨🇳
E-Da Hospital, Kaohsiung, Taiwan
🇨🇳National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan
🇨🇳Veterans General Hospital-Taipei, Taipei, Taiwan
The Effect of Lansoprazole in Combination With Ecabet Sodium for Gastroesophageal Reflux Disease
- Conditions
- Interventions
- First Posted Date
- 2009-12-25
- Last Posted Date
- 2011-07-28
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT01039558
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of Heartburn
- Conditions
- Interventions
- First Posted Date
- 2009-12-23
- Last Posted Date
- 2011-03-28
- Lead Sponsor
- Novartis
- Target Recruit Count
- 120
- Registration Number
- NCT01037452
An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis
- First Posted Date
- 2009-11-06
- Last Posted Date
- 2013-08-13
- Lead Sponsor
- Janssen Korea, Ltd., Korea
- Target Recruit Count
- 217
- Registration Number
- NCT01008696
Study Evaluating The Potential Effect Of Lansoprazole On The Pharmacokinetics Of Bosutinib In Healthy Subjects
- First Posted Date
- 2009-08-06
- Last Posted Date
- 2011-04-19
- Lead Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 24
- Registration Number
- NCT00952913
- Locations
- 🇺🇸
Pfizer Investigational Site, Miami, Florida, United States
Comparison of Prilosec Over-the-counter (OTC)® Versus Prevacid® for Gastric Acid Suppression
- Conditions
- Interventions
- First Posted Date
- 2009-05-18
- Last Posted Date
- 2010-12-31
- Lead Sponsor
- Procter and Gamble
- Target Recruit Count
- 40
- Registration Number
- NCT00903448
- Locations
- 🇺🇸
Research Site, Oklahoma City, Oklahoma, United States
Twice Daily Prevacid for the Treatment of Laryngopharyngeal Reflux
- First Posted Date
- 2009-03-18
- Last Posted Date
- 2017-03-27
- Lead Sponsor
- University of California, Davis
- Target Recruit Count
- 59
- Registration Number
- NCT00864396
- Locations
- 🇺🇸
University of California Davis Medical Center, Sacramento, California, United States
Drug Development Updates
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