MedPath

LY-3300054

Generic Name
LY-3300054

A Study of Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Cancer
Interventions
First Posted Date
2018-04-12
Last Posted Date
2021-04-15
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
17
Registration Number
NCT03495323
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

A Study of LY3381916 Alone or in Combination With LY3300054 in Participants With Solid Tumors

Phase 1
Terminated
Conditions
Solid Tumor
Non Small Cell Lung Cancer
Renal Cell Carcinoma
Triple Negative Breast Cancer
Interventions
First Posted Date
2017-11-17
Last Posted Date
2020-06-09
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
60
Registration Number
NCT03343613
Locations
🇺🇸

IU Simon Cancer Center, Indianapolis, Indiana, United States

🇺🇸

Tennessee Oncology PLLC, Nashville, Tennessee, United States

🇫🇷

Gustave Roussy, Villejuif Cedex, France

and more 9 locations

A Study of LY3321367 Alone or With LY3300054 in Participants With Advanced Relapsed/Refractory Solid Tumors

Phase 1
Completed
Conditions
Solid Tumor
Interventions
First Posted Date
2017-04-04
Last Posted Date
2023-10-17
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
209
Registration Number
NCT03099109
Locations
🇪🇸

Fundación Jiménez Díaz-Oncology, Madrid, Spain

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇰🇷

Severance Hospital Yonsei University Health System, Seoul, Korea, Republic of

and more 12 locations

A Study of LY3200882 in Participants With Solid Tumors

Phase 1
Active, not recruiting
Conditions
Solid Tumor
Interventions
First Posted Date
2016-10-18
Last Posted Date
2025-04-18
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
223
Registration Number
NCT02937272
Locations
🇦🇺

St Vincent's Hospital Sydney, Sydney, New South Wales, Australia

🇦🇺

Greenslopes Private Hospital, Greenslopes, Queensland, Australia

🇫🇷

CHRU de Lille, Lille, France

and more 15 locations

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Phase 1
Active, not recruiting
Conditions
Cutaneous Melanoma
Pancreatic Cancer
Solid Tumor
Microsatellite Instability-High (MSI-H) Solid Tumors
Breast Cancer (HR+HER2-)
Interventions
First Posted Date
2016-06-06
Last Posted Date
2024-05-31
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
215
Registration Number
NCT02791334
Locations
🇪🇸

Hospital Madrid Norte Sanchinarro, Madrid, Spain

🇨🇳

National Cheng Kung University Hospital, Tainan, Taiwan

🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

and more 11 locations
© Copyright 2025. All Rights Reserved by MedPath