MedPath

Sintilimab

Generic Name
Sintilimab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2072873-06-2
Unique Ingredient Identifier
8FU7FQ8UPK
Associated Conditions
-
Associated Therapies
-

Orelabrutinib and Sintilimab in Relapsed or Refractory Central Nervous System Lymphoma

Phase 1
Recruiting
Conditions
Primary Central Nervous System Hodgkin Lymphoma
Interventions
First Posted Date
2021-07-14
Last Posted Date
2022-11-08
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Target Recruit Count
48
Registration Number
NCT04961515
Locations
🇨🇳

2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

A Study of Sintilimab in Combination With Axitinib in Advanced Renal Cell Cancer

Phase 2
Not yet recruiting
Conditions
Clear Cell Renal Cell Carcinoma
Renal Cell Carcinoma
Interventions
First Posted Date
2021-07-12
Last Posted Date
2021-07-12
Lead Sponsor
Tianjin Medical University Second Hospital
Target Recruit Count
40
Registration Number
NCT04958473
Locations
🇨🇳

Tianjin Medical Unversity Second Hospital, Tianjin, Tianjin, China

TACE Combined with Sintilimab Plus Bevacizumab Biosimilar in Patients with Advanced Hepatocellular Carcinoma (TASK-02)

Phase 2
Completed
Conditions
Hepatocellular Carcinoma
Interventions
Drug: Sintilimab
Combination Product: TACE
First Posted Date
2021-07-08
Last Posted Date
2024-10-31
Lead Sponsor
Fudan University
Target Recruit Count
29
Registration Number
NCT04954794
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, China

IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC

Phase 1
Completed
Conditions
NPC
Interventions
Drug: Sintilimab
Drug: IBI310
First Posted Date
2021-06-30
Last Posted Date
2023-02-23
Lead Sponsor
Innovent Biologics (Suzhou) Co. Ltd.
Target Recruit Count
30
Registration Number
NCT04945421
Locations
🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Neoadjuvant Safety of Sintilimab + XELOX + Bevacizumab in PMMR/MSS CRLM Patients

Phase 1
Active, not recruiting
Conditions
Colorectal Cancer Metastatic
Interventions
First Posted Date
2021-06-25
Last Posted Date
2024-12-03
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
36
Registration Number
NCT04940546
Locations
🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Adjuvant Chemotherapy and Anti-PD-1 Antibody in Patients With Stage IIIC2-IVB Cervical Cancer

Phase 2
Recruiting
Conditions
Cervical Cancer
Interventions
First Posted Date
2021-06-09
Last Posted Date
2021-06-09
Lead Sponsor
Taizhou Hospital
Target Recruit Count
50
Registration Number
NCT04918628
Locations
🇨🇳

Youyou Xie, Taizhou, Zhejiang, China

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

Phase 1
Active, not recruiting
Conditions
Total Neoadjuvant Treatment
Locally Advanced Rectal Cancer
PD-1
Tislelizumab
Interventions
First Posted Date
2021-05-28
Last Posted Date
2023-11-18
Lead Sponsor
The First Hospital of Jilin University
Target Recruit Count
46
Registration Number
NCT04906044
Locations
🇨🇳

First Hospital of Jilin University, Changchun, Jilin, China

Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma

Phase 2
Conditions
Primary Central Nervous System Lymphoma
Interventions
First Posted Date
2021-05-24
Last Posted Date
2021-05-24
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
32
Registration Number
NCT04899427
Locations
🇨🇳

Wei Zhang, Beijing, Beijing, China

Sintilimab and Nimotuzumab Combined With Chemotherapy for the Treatment of R/M HNSCC.

Phase 2
Conditions
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Interventions
Drug: Nimotuzumab
Drug: Sintilimab
Drug: Chemotherapy drug
First Posted Date
2021-05-12
Last Posted Date
2021-05-12
Lead Sponsor
The First Affiliated Hospital of Soochow University
Target Recruit Count
100
Registration Number
NCT04882462

The Efficacy and Safety of Sintilimab Plus Anlotinib Combined With Chemotherapy as Neoadjuvant Therapy in TNBC

First Posted Date
2021-05-07
Last Posted Date
2023-11-08
Lead Sponsor
Guangdong Provincial People's Hospital
Target Recruit Count
31
Registration Number
NCT04877821
Locations
🇨🇳

NeoSACT, Guangzhou, Guangdong, China

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