Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
Which Supraesophageal Reflux Symptoms Reliably Respond to Proton-Pump-Inhibitor (PPI) Therapy
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2011-12-15
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 500
- Registration Number
- NCT00170001
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Symptomatic Gastroesophageal Reflux Disease: Double Blind Randomized Controlled Study of On-demand Therapy Versus Maintenance Therapy
- Conditions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2010-03-30
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 244
- Registration Number
- NCT00164840
- Locations
- 🇨🇳
Endoscopy Centre, Prince of Wales Hospital, Hong Kong, China
Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis
- First Posted Date
- 2005-07-25
- Last Posted Date
- 2008-01-16
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 30
- Registration Number
- NCT00123656
- Locations
- 🇺🇸
University of Utah HSC, Salt Lake City, Utah, United States
Proton Pump Inhibitor Treatment Stop
- Conditions
- Interventions
- First Posted Date
- 2005-07-15
- Last Posted Date
- 2009-10-06
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 171
- Registration Number
- NCT00120315
- Locations
- 🇩🇰
Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark
Study of Acid Reflux in Asthma
- Conditions
- Interventions
- First Posted Date
- 2003-10-03
- Last Posted Date
- 2012-12-19
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Target Recruit Count
- 403
- Registration Number
- NCT00069823
- Locations
- 🇺🇸
Ohio State University, Columbus, Ohio, United States
🇺🇸Northern New England Consortium, Colchester, Vermont, United States
🇺🇸University of Miami, Miami, Florida, United States
Drug Development Updates
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