Naproxen
- Generic Name
- Naproxen
- Brand Names
- Aleve, Aleve PM, Aleve-D, Anaprox, Naprelan, Naprosyn, Sallus, Sudafed Sinus & Pain, Treximet, Vimovo
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14O3
- CAS Number
- 22204-53-1
- Unique Ingredient Identifier
- 57Y76R9ATQ
- Background
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its overall tolerability and effectiveness, nap...
- Indication
Naproxen is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and for the relief of mild to moderate pain. Further, it is first-line therapy for osteoarthritis, acute gouty arthritis, dysmenorrhea, and musculoskelet...
- Associated Conditions
- Acute Gouty Arthritis, Acute Migraine, Ankylosing Spondylitis (AS), Back pain, Bursitis, Extra-Articular Rheumatism, Fever, Flu caused by Influenza, Headache, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Muscle Spasms, Nasal Congestion, Osteoarthritis (OA), Pain, Post Traumatic Pain, Postoperative pain, Primary Dysmenorrhoea, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Seasonal Allergic Rhinitis, Sinusitis, Tendinitis, Toothache, Articular inflammation
- Associated Therapies
- -
A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or Knee
- Conditions
- Interventions
- First Posted Date
- 2005-10-18
- Last Posted Date
- 2015-06-19
- Target Recruit Count
- 581
- Registration Number
- NCT00240773
Oral vs Rectal Admin of Naproxen for Post-Vag Perineal Pain Control
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2007-11-15
- Lead Sponsor
- University of Saskatchewan
- Target Recruit Count
- 60
- Registration Number
- NCT00222976
- Locations
- 🇨🇦
Department of Anesthesia, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population
- Conditions
- First Posted Date
- 2005-08-29
- Last Posted Date
- 2021-03-03
- Target Recruit Count
- 605
- Registration Number
- NCT00137033
- Locations
- 🇺🇸
Pfizer Investigational Site, Chesapeake, Virginia, United States
A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)
- Conditions
- First Posted Date
- 2000-02-29
- Last Posted Date
- 2009-12-11
- Lead Sponsor
- National Institute on Aging (NIA)
- Registration Number
- NCT00004845
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸Medical University of South Carolina, North Charleston, South Carolina, United States
🇺🇸University of California Irvine Institute for Brain Aging and Dementia, Irvine, California, United States
Drug Development Updates
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