Mycophenolic acid
- Generic Name
- Mycophenolic acid
- Brand Names
- Myfortic
- Drug Type
- Small Molecule
- Chemical Formula
- C17H20O6
- CAS Number
- 24280-93-1
- Unique Ingredient Identifier
- HU9DX48N0T
- Background
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacroli...
- Indication
Mycophenolic acid is an antimetabolite immunosuppressant indicated for prophylaxis of organ rejection in adult patients receiving kidney transplants and in pediatric patients at least 5 years of age and older who are at least 6 months post kidney transplant. Mycophenolic acid is used in combination with cyclosporine and corticosteroids.
- Associated Conditions
- Kidney Transplant Rejection
- Associated Therapies
- -
Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen
- Conditions
- Interventions
- First Posted Date
- 2007-08-10
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 802
- Registration Number
- NCT00514514
- Locations
- 🇨🇭
Novartis Investigative Site, Bern, Switzerland
Myfortic in Heart Transplant Patients With Gastrointestinal (GI) Symptoms
- First Posted Date
- 2007-05-03
- Last Posted Date
- 2008-10-17
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 100
- Registration Number
- NCT00468936
- Locations
- 🇨🇦
McGill University Health Centre, Montreal, Quebec, Canada
Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients
- First Posted Date
- 2006-11-23
- Last Posted Date
- 2020-12-17
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 215
- Registration Number
- NCT00403416
- Locations
- 🇨🇭
Inselspital Bern, Bern, Switzerland
🇮🇹Azienda Ospedaliera di Padova - Universita degli Studi, Padova, Italy
🇺🇸University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
A Prospective Study on the Tolerability and Efficacy of the de Novo Use of Myfortic in Liver Transplant Recipients
- First Posted Date
- 2006-06-14
- Last Posted Date
- 2017-03-09
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 30
- Registration Number
- NCT00336817
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Conversion of CellCept to Myfortic: A Prospective Study in Liver Transplant Recipients
- First Posted Date
- 2006-06-14
- Last Posted Date
- 2016-11-06
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 29
- Registration Number
- NCT00336895
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Desensitization of Renal Transplant Candidates
- First Posted Date
- 2006-03-03
- Last Posted Date
- 2012-07-25
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 9
- Registration Number
- NCT00298883
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
Myfortic - Treatment for Extensive cGvHD
- Conditions
- Interventions
- First Posted Date
- 2006-03-02
- Last Posted Date
- 2015-04-03
- Target Recruit Count
- 34
- Registration Number
- NCT00298324
- Locations
- 🇩🇪
University Regensburg, Regensburg, Germany
🇪🇸Hospital Clínico Universitario, Valencia, Spain
🇨🇭University Hospital, Basel, Switzerland
Mycophenolate for Pulmonary Sarcoidosis
- Conditions
- First Posted Date
- 2005-12-06
- Last Posted Date
- 2018-06-18
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 20
- Registration Number
- NCT00262132
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
Enteric Coated Myfortic for Liver Transplant Recipients
- Conditions
- Locations
- 🇺🇸
Memorial Hermann Hospital, Houston, Texas, United States
Pharmacokinetics of Mycophenolate Mofetil in Healthy Volunteers
- Conditions
- First Posted Date
- 2005-08-10
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 130
- Registration Number
- NCT00128947
- Locations
- 🇺🇸
National Institutes of Health Clinical Center (CC), Bethesda, Maryland, United States
Drug Development Updates
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