Heparin
- Generic Name
- Heparin
- Brand Names
- Heparin Leo
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9005-49-6
- Unique Ingredient Identifier
- T2410KM04A
- Background
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (fac...
- Indication
Unfractionated heparin is indicated for prophylaxis and treatment of venous thrombosis and its extension, prevention of post-operative deep venous thrombosis and pulmonary embolism and prevention of clotting in arterial and cardiac surgery. In cardiology, it is used to prevent embolisms in patients with atrial fibrillation and as an adjunct antithrombin ther...
- Associated Conditions
- Blunt Injury, Clotting, Coagulopathy, Consumption, Contusions, Deep vein thrombosis postoperative, Disseminated Intravascular Coagulation (DIC), External Hemorrhoid, Inflammation, Inflammatory, non-infectious pruritic dermatosis, Interstitial Cystitis, Post procedural pulmonary embolism, Pulmonary Embolism, ST Segment Elevation Myocardial Infarction (STEMI), Sprains, Thromboembolism, Unstable Angina Pectoris, Venous Thrombosis (Disorder), Hematomas, Peripheral arterial embolism, Thromboembolic phenomena, Varicosities of the great saphenous vein
- Associated Therapies
- Circulation, Extracorporeal, Dialysis therapy, Transfusions, Maintenance of patency of IV injection devices
Comparison of Subcutaneous Heparin and Enoxaparin for Deep Venous Thrombosis (DVT) Prophylaxis in Surgical Intensive Care Patients
- Conditions
- Interventions
- First Posted Date
- 2011-03-30
- Last Posted Date
- 2013-05-20
- Lead Sponsor
- Lisa Louwers
- Registration Number
- NCT01325779
- Locations
- 🇺🇸
William Beaumont Hospital, Royal Oak, Michigan, United States
Effect of Heparin on Femoral Arterial Sheaths Thrombosis During Diagnostic Coronary Angiography
- First Posted Date
- 2010-12-15
- Last Posted Date
- 2010-12-15
- Target Recruit Count
- 304
- Registration Number
- NCT01260519
- Locations
- 🇸🇦
Prince Sultan Cardiac Center, Riyadh, Central, Saudi Arabia
Safety of Heparin in Patients With Septic Shock
- First Posted Date
- 2010-11-04
- Last Posted Date
- 2014-05-20
- Lead Sponsor
- University of Colorado, Denver
- Registration Number
- NCT01234285
- Locations
- 🇺🇸
University of Colorado Hospital, Aurora, Colorado, United States
Ethanol in the Prevention of Central Venous Catheter Infections
- Conditions
- Interventions
- First Posted Date
- 2010-10-28
- Last Posted Date
- 2012-07-17
- Lead Sponsor
- Hospital General Universitario Gregorio Marañon
- Target Recruit Count
- 200
- Registration Number
- NCT01229592
- Locations
- 🇪🇸
Servicio de Microbiología y Enfermedades Infecciosas. Hospital GU Gregorio Marañon, Madrid, Spain
Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients.
- Conditions
- Interventions
- First Posted Date
- 2010-10-26
- Last Posted Date
- 2010-10-26
- Lead Sponsor
- University Hospital, Antwerp
- Target Recruit Count
- 250
- Registration Number
- NCT01228292
- Locations
- 🇧🇪
Critical Care Department of the Antwerp University Hospital, Belgium, Edegem, Belgium
The Effect of Heparin in Treatment IVF-ET Failure
- First Posted Date
- 2010-10-05
- Last Posted Date
- 2010-10-05
- Lead Sponsor
- Yazd Medical University
- Target Recruit Count
- 86
- Registration Number
- NCT01214772
- Locations
- 🇮🇷
Yazd Research and Clinical Centre for Infertility, Yazd, Iran, Islamic Republic of
Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
- Conditions
- Interventions
- First Posted Date
- 2010-09-17
- Last Posted Date
- 2017-02-14
- Lead Sponsor
- Jan Stam, MD, PhD
- Target Recruit Count
- 67
- Registration Number
- NCT01204333
- Locations
- 🇳🇱
University Medical Centre Groningen, Groningen, Netherlands
🇵🇹Hospital de Santo António, Porto, Portugal
🇳🇱St. Antonius hospital, Nieuwegein, Netherlands
ULTrasound Accelerated ThrombolysIs of PulMonAry Embolism
- Conditions
- Interventions
- First Posted Date
- 2010-07-21
- Last Posted Date
- 2021-07-19
- Lead Sponsor
- Boston Scientific Corporation
- Target Recruit Count
- 59
- Registration Number
- NCT01166997
- Locations
- 🇨🇭
Inselspital Bern, Kliniken fur Kardiologie and Angiologie, Bern, Switzerland
🇩🇪Klinikum Dortmund gGmbH, Dortmund, Germany
🇩🇪Universitätsklinikum Heidelberg, Heidelberg, Germany
Study to Characterize the Effect of Heparin on Palifermin Activity
- First Posted Date
- 2010-07-15
- Last Posted Date
- 2014-11-06
- Lead Sponsor
- Swedish Orphan Biovitrum
- Target Recruit Count
- 44
- Registration Number
- NCT01163097
- Locations
- 🇺🇸
New Orleans Center for Clinical Research (NOCCR), Knoxville, Tennessee, United States
European Ambulance Acute Coronary Syndrome (ACS) Angiography Trial
- First Posted Date
- 2010-03-16
- Last Posted Date
- 2016-02-12
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 2198
- Registration Number
- NCT01087723
- Locations
- 🇦🇹
Magistratsabeilung 70, Wiener, Wien, Austria
🇦🇹Universitats-Klinik Fur, Wien, Austria
🇩🇰Odense Universitets Hospital, Odense, Denmark
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.