MedPath

Citric acid

Generic Name
Citric acid
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, As 3, Citrasate, Clenpiq, Cpda-1 Blood Collection System, Cytra-K, EnLyte, Hemosate Ultra, Leukotrap, Oracit, Phexxi, Pico-salax, Picoflo, Purg-odan, Renacidin
Drug Type
Small Molecule
Chemical Formula
C6H8O7
CAS Number
77-92-9
Unique Ingredient Identifier
XF417D3PSL
Background

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.

Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.

Associated Conditions
Acidosis, Catheter site calcification caused by appetite, Catheter site calcification caused by struvite, Gout, Headache, Heartburn, Kidney Stones, Metabolic Acidosis
Associated Therapies
Blood Specimen Collection, Blood sample storage, Bowel Preparation for Colonoscopy, Bowel preparation therapy, Chemical contraception, Potassium placement, Urine alkalinization therapy, Oral antisepsis

Characterization of Bovine Adrenal Medulla as a Model of Non-histaminergic Itch

Not Applicable
Completed
Conditions
Itch
Interventions
Drug: CA and BAM8-22
Drug: Vehicle and BAM8-22 application
Drug: vehicle
First Posted Date
2023-09-14
Last Posted Date
2023-09-14
Lead Sponsor
Aalborg University
Target Recruit Count
25
Registration Number
NCT06036589
Locations
🇩🇰

Aalborg University, Aalborg, Denmark

Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome

Early Phase 1
Recruiting
Conditions
Bacterial Vaginosis
Vulvovaginal Candidiasis
Interventions
First Posted Date
2023-03-03
Last Posted Date
2023-03-03
Lead Sponsor
Queen's Medical Center
Target Recruit Count
22
Registration Number
NCT05753813
Locations
🇺🇸

Queens Medical Center, 1004 Clinic POB1, Honolulu, Hawaii, United States

TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

Phase 4
Recruiting
Conditions
Colorectal Neoplasms
Surgery
Interventions
Drug: Fleet Enema
First Posted Date
2021-12-08
Last Posted Date
2024-08-27
Lead Sponsor
Nova Scotia Health Authority
Target Recruit Count
66
Registration Number
NCT05148494
Locations
🇨🇦

Victoria General Hospital, Halifax, Nova Scotia, Canada

Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients.

Not Applicable
Conditions
Head and Neck Cancer
Interventions
Device: low level laser
First Posted Date
2021-01-08
Last Posted Date
2021-01-08
Lead Sponsor
Nada Yousef
Target Recruit Count
60
Registration Number
NCT04700475
Locations
🇪🇬

Cairo university, Giza, Egypt

Study Assessing CLENPIQ As Bowel Preparation for Pediatric Colonoscopy

Phase 1
Recruiting
Conditions
Bowel Preparation
Interventions
First Posted Date
2019-10-02
Last Posted Date
2025-02-05
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT04113382
Locations
🇺🇸

Ferring Investigational Site, Bronx, New York, United States

A Cross-sectional Study to Measure Cough in Severe Asthma

Not Applicable
Completed
Conditions
Asthma
Cough
Interventions
Device: Leicester Cough monitor
Other: fractional exhaled nitric oxide testing (FeNO)
Other: Patient reported outcome measures
First Posted Date
2019-06-26
Last Posted Date
2023-11-22
Lead Sponsor
Queen's University, Belfast
Target Recruit Count
61
Registration Number
NCT03999203
Locations
🇬🇧

Queen's University Belfast, Belfast, United Kingdom

The Influence of Citric Acid Bone Surface Etching and Bone Defect Fill on GCF BMP-2 Release Profile

Phase 4
Completed
Conditions
Intrabony Periodontal Defect
Interventions
Drug: Control Test
First Posted Date
2018-12-07
Last Posted Date
2018-12-07
Lead Sponsor
Ain Shams University
Target Recruit Count
20
Registration Number
NCT03769402

Comparison of Clenpiq vs Golytely Bowel Preparation

Phase 4
Terminated
Conditions
Bowel Preparation Solutions
Interventions
First Posted Date
2017-06-26
Last Posted Date
2021-03-04
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
14
Registration Number
NCT03198221
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

The Efficacy and Safety of Caffeic Acid for Esophageal Cancer

Phase 3
Conditions
Esophagus Cancer
Interventions
Drug: placebo group
First Posted Date
2017-03-03
Last Posted Date
2020-11-27
Lead Sponsor
The First Affiliated Hospital of Henan University of Science and Technology
Target Recruit Count
300
Registration Number
NCT03070262
Locations
🇨🇳

The Clinical Medical College, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Henan, China

The Diagnostic Validity of the Urea Breath Test

Not Applicable
Completed
Conditions
Helicobacter Pylori Infection
Interventions
First Posted Date
2015-02-10
Last Posted Date
2019-04-18
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
1200
Registration Number
NCT02359942
Locations
🇰🇷

Seoul National University Hospital, Seongnam, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath