Nystatin
- Generic Name
- Nystatin
- Brand Names
- Flagystatin, Mycostatin, Nyaderm, Nyamyc, Nystop, Viaderm Kc
- Drug Type
- Small Molecule
- Chemical Formula
- C47H75NO17
- CAS Number
- 1400-61-9
- Unique Ingredient Identifier
- W1LX4T91WI
- Background
Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of Streptomyces noursei, and is closely related to amphotericin B, differing only slightly in str...
- Indication
Nystatin is available in oral formulations for the treatment and/or prevention of oral candidiasis (a.k.a. thrush), intestinal candidiasis, and anal candidiasis. It is indicated topically for the treatment of vulvovaginal candidiasis and other cutaneous candida infections. A combination product containing nystatin alongside neomycin, gramicidin D, and triamc...
- Associated Conditions
- Anal candidiasis, Intestinal Candidiasis, Invasive Candidiasis, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Oral Candidiasis, Pruritus Ani, Pruritus Vulvae, Skin candida, Trichomonas Vaginitis, Vaginal Candidiasis, Vulvovaginal Candidiasis, Corticosteroid-responsive dermatoses, Cutaneous candidiasis
- Associated Therapies
- -
Curcumin; Rose Bengal; Denture Stomatitis
- Conditions
- Interventions
- First Posted Date
- 2021-04-08
- Last Posted Date
- 2021-04-08
- Lead Sponsor
- King Saud University
- Target Recruit Count
- 45
- Registration Number
- NCT04837664
- Locations
- 🇸🇦
King Saud University, Riyadh, Saudi Arabia
Effects of Nystatin Suspension Oral Application on Oral Microbial Community
- First Posted Date
- 2020-09-16
- Last Posted Date
- 2022-06-15
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 20
- Registration Number
- NCT04550546
- Locations
- 🇺🇸
Eastman Dental Institute, Rochester, New York, United States
Clinical Trial Evaluating Chlorine e6 Derivative-mediated Antimicrobial Photodynamic Therapy as a Treatment for Denture Stomatitis
- Conditions
- Interventions
- First Posted Date
- 2020-08-31
- Last Posted Date
- 2020-08-31
- Lead Sponsor
- São Paulo State University
- Target Recruit Count
- 65
- Registration Number
- NCT04532060
Fecal Transplant +/- Gut Decontamination in Preventing Acute Graft Versus Host Disease in Patients Given Broad-Spectrum Antibiotics
- Conditions
- Interventions
- First Posted Date
- 2019-03-05
- Last Posted Date
- 2020-03-04
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT03862079
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
- Conditions
- Interventions
- First Posted Date
- 2017-06-06
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- Astellas Institute for Regenerative Medicine
- Target Recruit Count
- 42
- Registration Number
- NCT03178149
- Locations
- 🇺🇸
Retina Specialty Institute, Pensacola, Florida, United States
🇺🇸Emory University Eye Center, Atlanta, Georgia, United States
🇺🇸Retina Consultants of Southwest Florida & National Ophthalmic Research Institute, Fort Myers, Florida, United States
Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers
- Conditions
- Interventions
- First Posted Date
- 2014-06-18
- Last Posted Date
- 2014-06-19
- Lead Sponsor
- Jagiellonian University
- Target Recruit Count
- 80
- Registration Number
- NCT02166450
- Locations
- 🇵🇱
Zbigniew Żak Voivodeship Dental Clinic, Krakow, Poland
🇵🇱Jagiellonian University Dental Clinic, Krakow, Poland
The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus
- Conditions
- Interventions
- First Posted Date
- 2012-12-06
- Last Posted Date
- 2015-12-11
- Lead Sponsor
- University of Copenhagen
- Target Recruit Count
- 25
- Registration Number
- NCT01743690
- Locations
- 🇩🇰
University of Copenhagen, Copenhagen, Denmark
Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants
- Conditions
- Interventions
- First Posted Date
- 2012-02-10
- Last Posted Date
- 2013-07-16
- Target Recruit Count
- 300
- Registration Number
- NCT01531192
- Locations
- 🇹🇷
Zekai Tahir Burak Maternity Teaching Hospital, Division of Neonatology, Ankara, Turkey
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
- Conditions
- Interventions
- First Posted Date
- 2011-12-19
- Last Posted Date
- 2017-04-05
- Lead Sponsor
- Policlinico Hospital
- Target Recruit Count
- 99
- Registration Number
- NCT01495039
- Locations
- 🇮🇹
Intensive care Unit, Policlinico Hospital Bari, Bari, Italy
Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer
- First Posted Date
- 2004-08-24
- Last Posted Date
- 2013-03-26
- Lead Sponsor
- Aronex Pharmaceuticals
- Registration Number
- NCT00002742
- Locations
- 🇺🇸
Scott and White Clinic, Temple, Texas, United States
🇺🇸Infections Limited, P.S., Tacoma, Washington, United States
🇺🇸Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.