Acarbose
- Generic Name
- Acarbose
- Brand Names
- Precose
- Drug Type
- Small Molecule
- Chemical Formula
- C25H43NO18
- CAS Number
- 56180-94-0
- Unique Ingredient Identifier
- T58MSI464G
- Background
Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex...
- Indication
Acarbose is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- Associated Conditions
- Type 2 Diabetes Mellitus
- Associated Therapies
- -
the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin
- First Posted Date
- 2015-05-08
- Last Posted Date
- 2015-05-08
- Lead Sponsor
- Shanghai 6th People's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02438397
- Locations
- 🇨🇳
the 6th affliliated hospital of Shanghai Jiaotong university, Shanghai, Shanghai, China
Effect of Acarbose on Postprandial Lipoprotein Levels in Glucose Intolerant Patients
- Conditions
- Interventions
- First Posted Date
- 2015-02-04
- Last Posted Date
- 2015-02-09
- Target Recruit Count
- 21
- Registration Number
- NCT02355509
- Locations
- 🇲🇽
Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, México City, Distrito Federal, Mexico
Combining Saxagliptin and Acarbose to Improve Postprandial Glycaemia in Type 2 Diabetes
- First Posted Date
- 2014-12-12
- Last Posted Date
- 2018-07-06
- Lead Sponsor
- Zilin Sun
- Target Recruit Count
- 22
- Registration Number
- NCT02315495
- Locations
- 🇨🇳
Department of Endocrinology, Zhongda Hospital. Institute of Diabetes, Southeast University, Nanjing, Jiangsu, China
24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy
- First Posted Date
- 2014-09-17
- Last Posted Date
- 2017-04-14
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 689
- Registration Number
- NCT02243176
- Locations
- 🇨🇳
Research Site, Shanghai, China
Relative Bioavailability of BI 44847 in Different Ethnic Groups and Evaluation of Effect of Diet and Acarbose Coadministration on Bioavailability Following Oral Administration of 200 mg BI 44847 in Healthy Male Volunteers
- First Posted Date
- 2014-08-08
- Last Posted Date
- 2014-08-08
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 37
- Registration Number
- NCT02211950
Efficacy and Safety of Mitiglinide vs Acarbose in Patients With Type 2 Diabetes Mellitus
- First Posted Date
- 2014-05-21
- Last Posted Date
- 2016-07-14
- Lead Sponsor
- Zhongda Hospital
- Target Recruit Count
- 248
- Registration Number
- NCT02143765
- Locations
- 🇨🇳
The First People's Hospital of Changzhou, Changzhou, Jiangsu, China
🇨🇳The Second People's Hospital of Huai'an, Huai'an, Jiangsu, China
🇨🇳Xuzhou Central Hospital, Xuzhou, Jiangsu, China
A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
- First Posted Date
- 2014-02-26
- Last Posted Date
- 2019-10-09
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 192
- Registration Number
- NCT02072096
- Locations
- 🇺🇸
Rocky Mountain Diabetes and Osteoporosis Center, Idaho Falls, Idaho, United States
🇺🇸Southern New Hampshire Diabetes and Endocrinology, Nashua, New Hampshire, United States
🇺🇸Carolina Health Specialists, Myrtle Beach, South Carolina, United States
Efficacy and Safety of Voglibose Compared With Acarbose in Participants With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2014-01-30
- Last Posted Date
- 2019-03-13
- Lead Sponsor
- Takeda
- Target Recruit Count
- 494
- Registration Number
- NCT02049814
Acarbose, Postprandial Hypotension and Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2014-01-23
- Last Posted Date
- 2017-06-28
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 15
- Registration Number
- NCT02043886
- Locations
- 🇨🇦
VITALiTY Research Centre, Vancouver, British Columbia, Canada
Acarbose and Older Adults With Postprandial Hypotension
- Conditions
- Interventions
- First Posted Date
- 2013-08-01
- Last Posted Date
- 2021-05-28
- Lead Sponsor
- Kenneth Madden
- Target Recruit Count
- 42
- Registration Number
- NCT01914133
- Locations
- 🇨🇦
Vancouver Coastal Health Research Institute, VGH Research Pavilion Room 186, Vancouver, British Columbia, Canada
Drug Development Updates
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