Verapamil
- Generic Name
- Verapamil
- Brand Names
- Calan, Isoptin, Tarka, Verelan
- Drug Type
- Small Molecule
- Chemical Formula
- C27H38N2O4
- CAS Number
- 52-53-9
- Unique Ingredient Identifier
- CJ0O37KU29
- Background
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like diltiazem and flunarizine, bu...
- Indication
Verapamil is indicated in the treatment of vasopastic (i.e. Prinzmetal's) angina, unstable angina, and chronic stable angina. It is also indicated to treat hypertension, for the prophylaxis of repetitive paroxysmal supraventricular tachycardia, and in combination with digoxin to control ventricular rate in patients with atrial fibrillation or atrial flutter....
- Associated Conditions
- Chronic Stable Angina Pectoris, Cluster Headache, Heart Rate, Hypertension, Paroxysmal Supraventricular Tachycardia (PSVT), Supra-ventricular Tachyarrhythmias, Unstable Angina Pectoris, Vasospastic Angina
- Associated Therapies
- -
Does Verapamil Given Orally Prevent Radial Artery Spasm During Transradial Coronary Angiography
- First Posted Date
- 2024-06-07
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- Mersin Medicalpark Hastanesi
- Target Recruit Count
- 150
- Registration Number
- NCT06447688
- Locations
- 🇹🇷
VM Medicalpark, Mersin, Turkey
Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin
- Conditions
- Interventions
- First Posted Date
- 2023-09-11
- Last Posted Date
- 2024-04-16
- Lead Sponsor
- Guangdong Raynovent Biotech Co., Ltd
- Target Recruit Count
- 56
- Registration Number
- NCT06031454
- Locations
- 🇨🇳
the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Targeting Beta Cell Dysfunction With Verapamil in Longstanding T1D
- First Posted Date
- 2023-05-06
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- Benaroya Research Institute
- Target Recruit Count
- 10
- Registration Number
- NCT05847413
- Locations
- 🇺🇸
Benaroya Research Institute, Seattle, Washington, United States
Dilution of Verapamil During Intraarterial Administration
- Conditions
- Interventions
- First Posted Date
- 2022-11-23
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- University of Illinois at Chicago
- Target Recruit Count
- 55
- Registration Number
- NCT05625503
- Locations
- 🇺🇸
University of Illinois Hospital, Chicago, Illinois, United States
Quinidine Versus Verapamil in Short-coupled Idiopathic Ventricular Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2022-10-25
- Last Posted Date
- 2023-09-13
- Target Recruit Count
- 24
- Registration Number
- NCT05593757
- Locations
- 🇳🇱
Academic Medical Center, Amsterdam, Noord-Holland, Netherlands
Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy
- Conditions
- Interventions
- First Posted Date
- 2022-10-06
- Last Posted Date
- 2024-06-14
- Lead Sponsor
- Morten Steen Kvistholm Jensen
- Target Recruit Count
- 100
- Registration Number
- NCT05569382
- Locations
- 🇩🇰
Department of Cardiology, Aarhus University Hospital, Aarhus N, Denmark
🇩🇰Department of Cardiology, Odense University Hospital, Odense, Denmark
🇩🇰Department of Cardiology, Zealand University Hospital, Roskilde, Denmark
A Study to Assess the Drug Interaction Between MYK-224 and Itraconazole and Verapamil in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2022-03-31
- Last Posted Date
- 2023-01-13
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 45
- Registration Number
- NCT05304533
- Locations
- 🇺🇸
Local Institution - 0001, Dallas, Texas, United States
Verapamil in Supraclavicular Brachial Plexus Block
- First Posted Date
- 2022-01-11
- Last Posted Date
- 2022-01-11
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT05183997
Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2021-03-10
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 135
- Registration Number
- NCT04790331
The EPIVER Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2020-10-05
- Last Posted Date
- 2024-04-29
- Target Recruit Count
- 104
- Registration Number
- NCT04573751
- Locations
- 🇷🇺
Cardiology Research Institute, Tomsk NRMC, Tomsk, Tomsk Region, Russian Federation
Drug Development Updates
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