Verapamil
- Generic Name
- Verapamil
- Brand Names
- Calan, Isoptin, Tarka, Verelan
- Drug Type
- Small Molecule
- Chemical Formula
- C27H38N2O4
- CAS Number
- 52-53-9
- Unique Ingredient Identifier
- CJ0O37KU29
- Background
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like diltiazem and flunarizine, bu...
- Indication
Verapamil is indicated in the treatment of vasopastic (i.e. Prinzmetal's) angina, unstable angina, and chronic stable angina. It is also indicated to treat hypertension, for the prophylaxis of repetitive paroxysmal supraventricular tachycardia, and in combination with digoxin to control ventricular rate in patients with atrial fibrillation or atrial flutter....
- Associated Conditions
- Chronic Stable Angina Pectoris, Cluster Headache, Heart Rate, Hypertension, Paroxysmal Supraventricular Tachycardia (PSVT), Supra-ventricular Tachyarrhythmias, Unstable Angina Pectoris, Vasospastic Angina
- Associated Therapies
- -
Atrioventricular Block and Cluster Headache (SEVA)
- First Posted Date
- 2020-05-28
- Last Posted Date
- 2023-01-25
- Lead Sponsor
- Centre Hospitalier Universitaire de Nice
- Target Recruit Count
- 60
- Registration Number
- NCT04406259
- Locations
- 🇫🇷
AP-HP Hôpital la Timone, Marseille, France
🇫🇷CHU de Nice, NICE Cedex 1, Chun, France
Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.
- Conditions
- Interventions
- First Posted Date
- 2020-04-22
- Last Posted Date
- 2021-12-03
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 135
- Registration Number
- NCT04356196
- Locations
- 🇪🇬
Faculty of medicine Assiut university, Assiut, Egypt
Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms
- First Posted Date
- 2020-04-17
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Nicolaus Copernicus University
- Target Recruit Count
- 804
- Registration Number
- NCT04351763
- Locations
- 🇵🇱
Nicolaus Copernicus University, Bydgoszcz, Poland
Adenosine Versus Verapamil for Management of Supraventricular Tachycardia Post- Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2019-12-18
- Last Posted Date
- 2020-12-02
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 268
- Registration Number
- NCT04203368
- Locations
- 🇪🇬
Ain Shams university, Cairo, Egypt
A Study to Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2018-12-20
- Last Posted Date
- 2024-04-22
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 82
- Registration Number
- NCT03782662
- Locations
- 🇬🇧
Richmond Pharmacology Ltd, London, United Kingdom
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
Verapamil for Neuroprotection in Stroke
- Conditions
- First Posted Date
- 2017-11-20
- Last Posted Date
- 2022-08-10
- Lead Sponsor
- Global Neurosciences Institute
- Target Recruit Count
- 20
- Registration Number
- NCT03347786
- Locations
- 🇺🇸
Crozer Keystone Health System, Upland, Pennsylvania, United States
This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men
- Conditions
- Interventions
- First Posted Date
- 2017-10-11
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 45
- Registration Number
- NCT03307252
- Locations
- 🇩🇪
CTC North GmbH & Co. KG, Hamburg, Hamburg, Germany
Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2021-07-01
- Lead Sponsor
- Theracos
- Target Recruit Count
- 48
- Registration Number
- NCT03296800
- Locations
- 🇺🇸
Covance Clinical Research Unit, Daytona Beach, Florida, United States
A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems
- Conditions
- Interventions
- First Posted Date
- 2017-04-04
- Last Posted Date
- 2021-03-22
- Target Recruit Count
- 18
- Registration Number
- NCT03098680
- Locations
- 🇬🇧
Addenbrooke's Hospital, Cambridge, Cambridgeshire, United Kingdom
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.