Toripalimab

Generic Name
Toripalimab
Brand Names
Loqtorzi
Drug Type
Biotech
Chemical Formula
-
CAS Number
1924598-82-2
Unique Ingredient Identifier
8JXN261VVA
Background

Toripalimab is under investigation in clinical trial NCT03919383 (Phase II of Lenvatinib Plus Toripalimab for Advanced HCC).

Indication

⑴用于治疗既往标准治疗失败后的局部进展或转移性黑色素瘤。⑵用于治疗既往接受过二线及以上系统治疗失败的复发/转移性鼻咽癌(NPC)。⑶用于治疗既往接受过治疗的局部进展或转移性尿路上皮癌(UC)。⑷用于食管鳞癌一线治疗。

Associated Conditions
-
Associated Therapies
-

Toripalimab Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-Cell Lymphoma

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2024-07-09
Last Posted Date
2024-07-09
Lead Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Target Recruit Count
43
Registration Number
NCT06492629
Locations
🇨🇳

Department of Medical Oncology, Beijing, Beijing, China

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

First Posted Date
2024-06-13
Last Posted Date
2024-11-05
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
100
Registration Number
NCT06457503
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell

First Posted Date
2024-06-04
Last Posted Date
2024-06-04
Lead Sponsor
Taizhou Hospital
Target Recruit Count
136
Registration Number
NCT06441344

Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH)

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-05-31
Last Posted Date
2024-05-31
Lead Sponsor
Shanghai Chest Hospital
Target Recruit Count
478
Registration Number
NCT06437977

Toripalimab for High-risk Locally Advanced Cervical Cancer

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2024-05-16
Last Posted Date
2024-05-16
Lead Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Target Recruit Count
130
Registration Number
NCT06416696
Locations
🇨🇳

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, Beijing, China

To Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With Toripalimab Sequential Chemotherapy as Neoadjuvant Treatment in Patients With HR-positive, HER2-low Breast Cancer

First Posted Date
2024-04-29
Last Posted Date
2024-05-23
Lead Sponsor
RemeGen Co., Ltd.
Target Recruit Count
79
Registration Number
NCT06389006
Locations
🇨🇳

Jiong Wu, Shanghai, Fudan University Shanghai Cancer Center, China

A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors

First Posted Date
2024-04-29
Last Posted Date
2024-04-29
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
48
Registration Number
NCT06389526

LM-108 in Combination With PD-1 Based Treatment for Patients With Recurrent or Metastatic Triple - Negative Breast Cancer

First Posted Date
2024-04-29
Last Posted Date
2024-08-02
Lead Sponsor
Fudan University
Target Recruit Count
74
Registration Number
NCT06387628
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-17
Last Posted Date
2024-04-17
Lead Sponsor
First Affiliated Hospital of Zhejiang University
Target Recruit Count
32
Registration Number
NCT06371274
Locations
🇨🇳

The first affiliated hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, P.R. China, China

Toripalimab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

First Posted Date
2024-04-12
Last Posted Date
2024-04-12
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
300
Registration Number
NCT06362317
Locations
🇨🇳

Chinese Academy of Medical Sciences & Peking Union Medical College Hospital (CAMS&PUMCH), Beijing, Beijing, China

© Copyright 2024. All Rights Reserved by MedPath