Lamivudine
- Generic Name
- Lamivudine
- Brand Names
- Cimduo, Combivir, Delstrigo, Dovato, Epivir, Epivir Hbv, Epzicom, Kivexa, Symfi, Triumeq, Trizivir, Zeffix, Lamivudine Teva Pharma B.V., Lamivudine Teva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H11N3O3S
- CAS Number
- 134678-17-4
- Unique Ingredient Identifier
- 2T8Q726O95
- Background
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
- Indication
For the treatment of HIV infection and chronic hepatitis B (HBV).
- Associated Conditions
- Chronic Hepatitis B Infection, Human Immunodeficiency Virus (HIV) Infections, Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- -
A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Weill Medical College of Cornell University
- Registration Number
- NCT00002407
- Locations
- 🇺🇸
Cornell AIDS Clinical Trials Unit, New York, New York, United States
A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 60
- Registration Number
- NCT00002183
- Locations
- 🇺🇸
UCSD, San Diego, California, United States
🇺🇸Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States
🇺🇸AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States
A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients With HIV-Associated Kidney Disease
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 24
- Registration Number
- NCT00002397
- Locations
- 🇺🇸
Mount Sinai Med Ctr, New York, New York, United States
Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 624
- Registration Number
- NCT00009061
- Locations
- 🇺🇸
North Jersey Community Research Initiative, Newark, New Jersey, United States
🇺🇸Nicholas Bellos, Dallas, Texas, United States
🇺🇸Therafirst Med Ctr, Fort Lauderdale, Florida, United States
A Study of a Combination of Four Drugs in Patients With Recent HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 30
- Registration Number
- NCT00002233
- Locations
- 🇺🇸
Aaron Diamond AIDS Rsch Ctr / Rockefeller Univ, New York, New York, United States
🇺🇸Miriam Hosp / Family Healthcare Ctr at SSTAR, Providence, Rhode Island, United States
Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 8
- Registration Number
- NCT00002451
- Locations
- 🇺🇸
Albany Med College, Albany, New York, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
🇺🇸SUNY at Stony Brook / Division of Infectious Diseases, Stony Brook, New York, United States
Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 210
- Registration Number
- NCT00008554
- Locations
- 🇺🇸
Ocean View Internal Medicine, Long Beach, California, United States
🇺🇸Saint Michael's Med Ctr, Newark, New Jersey, United States
🇺🇸Hillsborough County Health Dept, Tampa, Florida, United States
A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 825
- Registration Number
- NCT00002378
- Locations
- 🇺🇸
Northwestern Univ Med Ctr, Chicago, Illinois, United States
🇺🇸Lehigh Valley Hosp, Allentown, Pennsylvania, United States
🇺🇸North Texas Infectious Disease Consultants, Dallas, Texas, United States
A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-06-07
- Target Recruit Count
- 900
- Registration Number
- NCT00000919
- Locations
- 🇺🇸
Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States
🇺🇸Marin County Specialty Clinic, San Rafael, California, United States
🇺🇸Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr, Atlanta, Georgia, United States
A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2009-02-20
- Lead Sponsor
- Abbott
- Target Recruit Count
- 660
- Registration Number
- NCT00004583
- Locations
- 🇺🇸
Vanderbilt Univ Med Ctr, Nashville, Tennessee, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
🇺🇸Tower ID Med Associates, Los Angeles, California, United States
Drug Development Updates
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