Nitric Oxide

Generic Name
Nitric Oxide
Brand Names
Inomax, Kinox, Noxivent, INOmax
Drug Type
Small Molecule
Chemical Formula
NO
CAS Number
10102-43-9
Unique Ingredient Identifier
31C4KY9ESH
Background

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
...

Indication

For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure

Associated Conditions
Hypoxic Respiratory Failure
Associated Therapies
-

Inhaled Nitric Oxide (iNO) in Post-Pulmonary Embolism (Post-PE)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-06-10
Last Posted Date
2024-04-03
Lead Sponsor
Dr. Denis O'Donnell
Target Recruit Count
16
Registration Number
NCT04920695
Locations
🇨🇦

Respiratory Investigation Unit, Kingston General Hospital, Kingston, Ontario, Canada

Nitric Oxide During Cardiopulmonary Bypass in Adult Surgery

First Posted Date
2021-03-19
Last Posted Date
2021-10-08
Lead Sponsor
Rabin Medical Center
Target Recruit Count
300
Registration Number
NCT04807413
Locations
🇮🇱

Rabin Medical Center/Beilinson Campus, Petach Tikva, Israel

Vitamin C Versus Nitric Oxide in Prolonged Ventilation

First Posted Date
2020-06-02
Last Posted Date
2020-06-09
Lead Sponsor
King Abdul Aziz Specialist Hospital
Target Recruit Count
60
Registration Number
NCT04411160
Locations
🇸🇦

King abd el Aziz specialist hospital, Ta'if, Saudi Arabia

Inhaled Nitric Oxide for Preventing Progression in COVID-19

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2020-05-14
Last Posted Date
2022-04-19
Lead Sponsor
Tufts Medical Center
Target Recruit Count
10
Registration Number
NCT04388683
Locations
🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

High Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-05-11
Last Posted Date
2022-04-11
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
21
Registration Number
NCT04383002
Locations
🇨🇦

University Health Network, Toronto General Hospital, Toronto, Ontario, Canada

Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19

First Posted Date
2020-03-12
Last Posted Date
2022-11-01
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
70
Registration Number
NCT04305457
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Louisiana State University Health Shreveport, Shreveport, Louisiana, United States

🇺🇸

Providence HealthCare Network, Anchorage, Alaska, United States

Pulmonary Capillary Recruitment in Fontan Patients

First Posted Date
2020-03-03
Last Posted Date
2022-04-07
Lead Sponsor
Jewish General Hospital
Target Recruit Count
15
Registration Number
NCT04292483
Locations
🇨🇦

Jewish General Hospital, Montreal, Quebec, Canada

Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection

First Posted Date
2020-03-02
Last Posted Date
2020-03-24
Lead Sponsor
Xijing Hospital
Registration Number
NCT04290858

The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-01-18
Last Posted Date
2022-07-14
Lead Sponsor
University of Alberta
Target Recruit Count
20
Registration Number
NCT04231773
Locations
🇨🇦

Clinical Physiology Laboratory, Edmonton, Alberta, Canada

NO During CPB in Neonates to Reduce Risk of AKI

First Posted Date
2020-01-03
Last Posted Date
2024-03-22
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Target Recruit Count
40
Registration Number
NCT04216927
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

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