Propylthiouracil
- Generic Name
- Propylthiouracil
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C7H10N2OS
- CAS Number
- 51-52-5
- Unique Ingredient Identifier
- 721M9407IY
- Background
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
- Indication
Used to manage hyperthyroidism which is due to an overactive thyroid gland (Grave's disease).
- Associated Conditions
- Hyperthyroidism, Thyrotoxic crisis
- Associated Therapies
- -
Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE
- Conditions
- Interventions
- First Posted Date
- 2023-03-09
- Last Posted Date
- 2023-10-19
- Lead Sponsor
- Maastricht University
- Target Recruit Count
- 28
- Registration Number
- NCT05762146
- Locations
- 🇩🇪
University Hospital Essen, Department of Neurology, Essen, Germany
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
- Conditions
- Interventions
- First Posted Date
- 2021-11-12
- Last Posted Date
- 2021-11-12
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 36
- Registration Number
- NCT05118542
- Locations
- 🇮🇩
University of Indonesia, Jakarta Pusat, Jakarta, Indonesia
Antithyroid Drug Treatment of Thyrotoxicosis in Young People
- Conditions
- Interventions
- First Posted Date
- 2011-09-20
- Last Posted Date
- 2016-09-21
- Lead Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
- Target Recruit Count
- 81
- Registration Number
- NCT01436994
- Locations
- 🇬🇧
Royal Hospital for Sick Children, Glasgow, United Kingdom
🇬🇧Hereford Hospital, Hereford, United Kingdom
🇬🇧St Bart's Hospital, London, United Kingdom
The Effect of Early Total Thyroidectomy in the Course of Graves' Orbitopathy
- Conditions
- Interventions
- First Posted Date
- 2010-01-26
- Last Posted Date
- 2010-01-26
- Lead Sponsor
- Ankara University
- Target Recruit Count
- 40
- Registration Number
- NCT01056419
- Locations
- 🇹🇷
Ankara University, Medical School, Ibni Sina Hospital, Endocrinology and Metabolic Diseases Department, Ankara, Turkey
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.