Oteseconazole
- Generic Name
- Oteseconazole
- Brand Names
- Vivjoa
- Drug Type
- Small Molecule
- Chemical Formula
- C23H16F7N5O2
- CAS Number
- 1340593-59-0
- Unique Ingredient Identifier
- VHH774W97N
- Background
Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. By binding and inhibiting CYP51, oteseconazole is active against most microorganisms associated with recurrent vulvovaginal candi...
- Indication
Oteseconazole is an azole antifungal indicated to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are not of reproductive potential.
- Associated Conditions
- Recurrent Vulvovaginal Candidiasis
- Associated Therapies
- -
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
- First Posted Date
- 2014-10-17
- Last Posted Date
- 2020-11-04
- Lead Sponsor
- Viamet
- Target Recruit Count
- 259
- Registration Number
- NCT02267356
- Locations
- 🇺🇸
Skin Specialists, PC, Omaha, Nebraska, United States
🇺🇸DermResearch, Austin, Texas, United States
🇺🇸Coastal Carolina Research Center, Mount Pleasant, South Carolina, United States
A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
- First Posted Date
- 2014-10-17
- Last Posted Date
- 2019-10-15
- Lead Sponsor
- Viamet
- Target Recruit Count
- 254
- Registration Number
- NCT02267382
- Locations
- 🇺🇸
Clinical Trials Management LLC, Metairie, Louisiana, United States
🇺🇸New England Center for Clinical Research, Fall River, Massachusetts, United States
🇺🇸Women's Health Research Center, Plainsboro, New Jersey, United States
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Acute Vaginal Candidiasis (Yeast Infection)
- First Posted Date
- 2013-07-03
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- Viamet
- Target Recruit Count
- 55
- Registration Number
- NCT01891331
- Locations
- 🇺🇸
Healthcare Clinical Data, Inc, North Miami, Florida, United States
🇺🇸Harborview ID Research Clinic, Seattle, Washington, United States
🇺🇸SUNY Downstate Medical Center, Brooklyn, New York, United States
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Moderate - Severe Interdigital Tinea Pedis
- First Posted Date
- 2013-07-03
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- Viamet
- Target Recruit Count
- 50
- Registration Number
- NCT01891305
- Locations
- 🇺🇸
Oregon Dermatology & Research Center, Portland, Oregon, United States
🇺🇸FXM Research, Miramar, Florida, United States
🇺🇸Wake Research Associates, Raleigh, North Carolina, United States
Drug Development Updates
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