MedPath

Cefdinir

Generic Name
Cefdinir
Drug Type
Small Molecule
Chemical Formula
C14H13N5O5S2
CAS Number
91832-40-5
Unique Ingredient Identifier
CI0FAO63WC

Overview

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.

Background

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.

Indication

Cefdinir is indicated to treat acute bacterial otitis media, acute maxillary sinusitis, community-acquired (CA) pneumonia, acute bacterial exacerbations of chronic bronchitis, pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections in children and adults. The organisms susceptible to cefdinir have been listed below in addition to their associated clinical condition that may be treated with cefdinir. Various beta-lactamase producing organisms may be treated, as indicated in certain sections below. Respiratory Acute bacterial exacerbations of chronic bronchitis caused by Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae (penicillin-susceptible only), and Moraxella catarrhalis Community-acquired pneumonia caused by Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae (penicillin-susceptible only), and Moraxella catarrhalis Ear, nose, and throat Acute bacterial otitis media caused by Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae (penicillin-susceptible only) Tonsillitis caused by Streptococcus pyogenes Pharyngitis caused by Streptococcus pyogenes Acute maxillary sinusitis caused by Haemophilus pneumoniae and Streptococcus pneumoniae (penicillin-susceptible only), and Moraxella catarrhalis Skin and skin structure infections Uncomplicated skin and skin structure infections caused by Staphylococcus aureus and Streptococcus pyogenes

Associated Conditions

  • Acute Exacerbation of Chronic Bronchitis (AECB)
  • Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae
  • Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza
  • Acute Exacerbations of Chronic Bronchitis caused by Moraxella catarrhalis
  • Acute exacerbation of chronic bronchitis caused by Haemophilus parainfluenzae
  • Acute maxillary sinusitis
  • Acute maxillary sinusitis caused by H. influenzae
  • Acute maxillary sinusitis caused by M. catarrhalis
  • Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
  • Community Acquired Pneumonia (CAP)
  • Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
  • Pneumonia due to Haemophilus influenzae (H. influenzae)
  • Streptococcal Pharyngitis
  • Tonsillitis
  • Tonsillitis streptococcal
  • Uncomplicated Skin and Skin Structure Infections
  • Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
  • Acute otitis media caused by M. catarrhalis
  • Acute otitis media caused by S.pneumoniae
  • Bacterial otitis media caused by Haemophilus influenzae
  • Community aquired pneumonia caused by H. parainfluenzae
  • Community aquired pneumonia caused by M.catarrhalis

FDA Approved Products

cefdinir
Manufacturer:Preferred Pharmaceuticals Inc.
Route:ORAL
Strength:250 mg in 5 mL
Approved: 2024/03/21
NDC:68788-8062
Cefdinir
Manufacturer:Lupin Pharmaceuticals, Inc.
Route:ORAL
Strength:250 mg in 5 mL
Approved: 2020/05/22
NDC:68180-723
Cefdinir
Manufacturer:Proficient Rx LP
Route:ORAL
Strength:300 mg in 1 1
Approved: 2023/07/01
NDC:71205-224
Cefdinir
Manufacturer:Redpharm Drug, Inc.
Route:ORAL
Strength:300 mg in 1 1
Approved: 2023/02/03
NDC:67296-1448
Cefdinir
Manufacturer:Preferred Pharmaceuticals Inc.
Route:ORAL
Strength:300 mg in 1 1
Approved: 2024/03/21
NDC:68788-7339

Singapore Approved Products

No Singapore products found for this drug

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