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Samuraciclib

Generic Name
Samuraciclib
Drug Type
Small Molecule
Chemical Formula
C22H30N6O
CAS Number
1805833-75-3
Unique Ingredient Identifier
46D4HS9ODA
Background

Samuraciclib is under investigation in clinical trial NCT03363893 (Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies).

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2023-11-09
Last Posted Date
2025-03-06
Lead Sponsor
Pfizer
Target Recruit Count
11
Registration Number
NCT06125522
Locations
🇺🇸

Highlands Oncology Group, Springdale, Arkansas, United States

🇺🇸

UCHealth Poudre Valley Hospital, Fort Collins, Colorado, United States

🇺🇸

UCHealth Harmony, Fort Collins, Colorado, United States

and more 16 locations

A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants

Phase 2
Active, not recruiting
Conditions
Metastatic Breast Cancer
Locally Advanced Breast Cancer
Breast Cancer
Interventions
First Posted Date
2023-07-27
Last Posted Date
2025-02-21
Lead Sponsor
Carrick Therapeutics Limited
Target Recruit Count
60
Registration Number
NCT05963984
Locations
🇺🇸

Ocala Oncology Center PL DBA Florida Cancer Affiliates, Ocala, Florida, United States

🇺🇸

Mfsmc-Hjwci, Baltimore, Maryland, United States

🇺🇸

Saint Luke's Cancer Institute, Kansas City, Missouri, United States

and more 29 locations

A Study of Samuraciclib and Elacestrant in Participants With Metastatic or Locally Advanced HR+/HER2-negative Breast Cancer

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Metastatic Breast Cancer
Locally Advanced Breast Cancer
Interventions
First Posted Date
2023-07-27
Last Posted Date
2025-05-11
Lead Sponsor
Carrick Therapeutics Limited
Target Recruit Count
48
Registration Number
NCT05963997
Locations
🇺🇸

Site 38 - Northwestern University, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States

🇺🇸

Site 42 - Dana-Farber Cancer Institute, EDDC, Boston, Massachusetts, United States

🇺🇸

Site 35 - Cleveland Clinic, Taussig Cancer Institute, Cleveland, Ohio, United States

and more 20 locations

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Phase 1
Recruiting
Conditions
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Interventions
First Posted Date
2021-03-17
Last Posted Date
2025-05-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
316
Registration Number
NCT04802759
Locations
🇺🇸

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

🇮🇱

Rabin MC, Petach Tikva, Israel

🇮🇱

Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

and more 25 locations
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