MedPath

Tolterodine

Generic Name
Tolterodine
Brand Names
Detrol, Detrusitol
Drug Type
Small Molecule
Chemical Formula
C22H31NO
CAS Number
124937-51-5
Unique Ingredient Identifier
WHE7A56U7K
Background

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Associated Conditions
Urinary Urge Incontinence

MILADY: A Randomized, Placebo-controlled Safety and Efficacy Trial of SSR240600C in Treatment of Overactive Bladder or Urge Urinary Incontinence.

Phase 2
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2005-09-15
Last Posted Date
2012-02-02
Lead Sponsor
Sanofi
Target Recruit Count
118
Registration Number
NCT00174798
Locations
🇺🇸

Hudson Valley Urology Center, Kingston, New York, United States

🇺🇸

Hudson Valley Urology, Poughkeepsie, New York, United States

🇺🇸

Rockhill Medical Plaza, Kansas City, Missouri, United States

and more 19 locations

Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction

Phase 4
Completed
Conditions
Urinary Incontinence
First Posted Date
2005-09-07
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
830
Registration Number
NCT00147654
Locations
🇺🇸

Pfizer Investigational Site, Cheyenne, Wyoming, United States

Study to Determine The Effectiveness Of Detrusitol In Patients Diagnosed With OAB

Phase 4
Completed
Conditions
Urinary Incontinence
First Posted Date
2005-09-02
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
600
Registration Number
NCT00143377

Effect of Detrol LA on Overactive Bladder Symptoms, Sexual Quality of Life and Sexual Function in Women

Phase 4
Completed
Conditions
Urinary Incontinence
First Posted Date
2005-09-02
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
400
Registration Number
NCT00143481
Locations
🇺🇸

Pfizer Investigational Site, Morgantown, West Virginia, United States

Evaluate Efficacy and Safety Of Tolterodine Extended Release Capsule Compared With Tolterodine Immediate Release Tablet

Phase 3
Completed
Conditions
Urinary Incontinence
First Posted Date
2005-08-31
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
260
Registration Number
NCT00139724
Locations
🇨🇳

Pfizer Investigational Site, Shanghai, China

A Study to Measure the Effect of Tolterodine Extended Release on the Thickness of the Bladder Wall in Patients With Overactive Bladder

Phase 4
Completed
Conditions
Urinary Incontinence
First Posted Date
2005-08-29
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
80
Registration Number
NCT00137397
Locations
🇬🇧

Pfizer Investigational Site, Pl6 8Dh, United Kingdom

Behavior Enhances Drug Reduction of Incontinence (BE-DRI)

Not Applicable
Completed
Conditions
Urinary Incontinence (UI)
Interventions
Behavioral: Behavioral training
First Posted Date
2004-08-31
Last Posted Date
2013-06-17
Lead Sponsor
Carelon Research
Target Recruit Count
307
Registration Number
NCT00090584
Locations
🇺🇸

University of Maryland, Baltimore, Maryland, United States

🇺🇸

Oakwood Hospital and Medical Center, Royal Oak, Michigan, United States

🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

and more 6 locations
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