MedPath

Tolterodine

Generic Name
Tolterodine
Brand Names
Detrol, Detrusitol
Drug Type
Small Molecule
Chemical Formula
C22H31NO
CAS Number
124937-51-5
Unique Ingredient Identifier
WHE7A56U7K
Background

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Associated Conditions
Urinary Urge Incontinence

Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis

Not Applicable
Conditions
Prostatitis
Interventions
First Posted Date
2009-06-04
Last Posted Date
2009-06-05
Lead Sponsor
Chongqing Medical University
Target Recruit Count
30
Registration Number
NCT00913315
Locations
🇨🇳

Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China

Study of ONO-8539 in Patients With Overactive Bladder

Phase 2
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2009-04-06
Last Posted Date
2012-06-14
Lead Sponsor
Ono Pharmaceutical Co. Ltd
Target Recruit Count
435
Registration Number
NCT00876421

Assessment of Patient-reported Goal Attainment in the Treatment of Female Overactive Bladder

Phase 4
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2009-02-04
Last Posted Date
2013-05-30
Lead Sponsor
Samsung Medical Center
Target Recruit Count
56
Registration Number
NCT00836381
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

Solifenacin Succinate Versus Tolterodine 4mg Once Daily

Phase 3
Completed
Conditions
Urinary Bladder, Overactive
Interventions
First Posted Date
2008-12-04
Last Posted Date
2014-09-18
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
1355
Registration Number
NCT00802373

Special Investigation For Long Term Use Of Tolterodine (Regulatory Post Marketing Commitment Plan).

Completed
Conditions
Urinary Bladder, Overactive
Interventions
First Posted Date
2008-11-21
Last Posted Date
2012-07-09
Lead Sponsor
Pfizer
Target Recruit Count
374
Registration Number
NCT00795509

A Study to Test the Effects of Tolterodine Tartrate in Patients With Overactive Bladder (0000-107)

Phase 1
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2008-10-08
Last Posted Date
2018-02-22
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
20
Registration Number
NCT00768521

Investigation of Tolterodine, Pregabalin and a Tolterodine - Pregabalin Combination for the Treatment of Overactive Bladder

Phase 2
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2008-09-04
Last Posted Date
2009-12-21
Lead Sponsor
Pfizer
Target Recruit Count
188
Registration Number
NCT00746681
Locations
🇬🇧

Pfizer Investigational Site, Plymouth, United Kingdom

Exploring Predictors of Symptoms Relapse After Discontinuation of Treatment in Overactive Bladder (OAB) Patients

Phase 4
Completed
Conditions
Overactive Bladder
Interventions
First Posted Date
2008-08-08
Last Posted Date
2019-12-02
Lead Sponsor
KYU-SUNG LEE
Target Recruit Count
173
Registration Number
NCT00730535
Locations
🇰🇷

Samsung Medical Center, Irwon-dong, Seoul, Korea, Republic of

🇰🇷

Asan Medical Center, Ulsan College of Medicine, Seoul, Korea, Republic of

🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

and more 1 locations

Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2008-06-23
Last Posted Date
2012-08-02
Lead Sponsor
Novartis
Target Recruit Count
117
Registration Number
NCT00703703
Locations
🇺🇸

Investigative Site, Morgantown, West Virginia, United States

Study to Test the Long Term Safety and Efficacy of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder

Phase 3
Completed
Conditions
Urinary Bladder, Overactive
Interventions
First Posted Date
2008-06-03
Last Posted Date
2024-11-20
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
2792
Registration Number
NCT00688688
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