Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
Doxycycline in Treatment of Bleeding With Depot Medroxyprogesterone Acetate (DMPA)
- First Posted Date
- 2010-12-07
- Last Posted Date
- 2011-11-28
- Lead Sponsor
- Omar Mamdouh Shaaban
- Target Recruit Count
- 68
- Registration Number
- NCT01254799
- Locations
- 🇪🇬
Faculty of Medicine, Assiut, Egypt
Persistent Lyme Empiric Antibiotic Study Europe
- Conditions
- Interventions
- First Posted Date
- 2010-09-23
- Last Posted Date
- 2016-09-08
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 280
- Registration Number
- NCT01207739
- Locations
- 🇳🇱
Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
🇳🇱Sint Maartenskliniek, Nijmegen, Netherlands
Effects of Doxycycline on Persistent Symptoms Post-neuroborreliosis
- Conditions
- Interventions
- First Posted Date
- 2010-09-20
- Last Posted Date
- 2010-09-20
- Lead Sponsor
- Linkoeping University
- Target Recruit Count
- 15
- Registration Number
- NCT01205464
- Locations
- 🇸🇪
Clinic for Infectious Diseases, University Hospital, Linköping, Östergötland, Sweden
Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA)
- Conditions
- Interventions
- First Posted Date
- 2010-09-10
- Last Posted Date
- 2015-01-13
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 178
- Registration Number
- NCT01198509
- Locations
- 🇺🇸
NYU Hospital for Joint Diseases, New York, New York, United States
🇺🇸Bellevue Hospital, New York, New York, United States
Doxycycline Versus Standard Care to Prevent Seroma Formation
- First Posted Date
- 2010-08-26
- Last Posted Date
- 2015-04-14
- Lead Sponsor
- Northwell Health
- Registration Number
- NCT01188954
- Locations
- 🇺🇸
Staten Island University Hospital, Staten Island, New York, United States
Antibiotic Treatment of Multiple Erythema Migrans
- Conditions
- Interventions
- First Posted Date
- 2010-07-16
- Last Posted Date
- 2017-05-05
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 500
- Registration Number
- NCT01163994
- Locations
- 🇸🇮
UMC Ljubljana, Department of Infectious Diseases, Ljubljana, Slovenia
The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID)
- Conditions
- Interventions
- First Posted Date
- 2010-07-12
- Last Posted Date
- 2018-07-10
- Lead Sponsor
- Harold Wiesenfeld
- Target Recruit Count
- 233
- Registration Number
- NCT01160640
- Locations
- 🇺🇸
Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania, United States
🇺🇸Allegheny County Health Department Sexually Transmitted Diseases Clinic, Pittsburgh, Pennsylvania, United States
🇺🇸UPMC Mercy Hospital, Pittsburgh, Pennsylvania, United States
Trial of Doxycycline to Reduce Sputum MMP-9 Activity in Adult Cystic Fibrosis (CF) Patients
- First Posted Date
- 2010-04-28
- Last Posted Date
- 2017-03-06
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 40
- Registration Number
- NCT01112059
- Locations
- 🇺🇸
University of alabama at Birmingham, Birmingham, Alabama, United States
Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy
- Conditions
- Interventions
- First Posted Date
- 2009-12-11
- Last Posted Date
- 2016-11-03
- Lead Sponsor
- Peter Eickholz
- Target Recruit Count
- 61
- Registration Number
- NCT01030666
- Locations
- 🇩🇪
Dept. of Periodontology, Center of Dental, Oral, and Maxillofacial Medicine, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
🇩🇪Section of Periodontology, University Hospital Heidelberg, Heidelberg, Germany
Doxycycline Outcomes in Lupus Erythematosus
- First Posted Date
- 2009-11-16
- Last Posted Date
- 2012-03-30
- Lead Sponsor
- Johns Hopkins University
- Registration Number
- NCT01014260
- Locations
- 🇺🇸
Johns Hopkins University SOM. 1830 East Monument St, Ste 7500, Baltimore, Maryland, United States
Drug Development Updates
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