Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
Antibiotic Treatment of Gulf War Veterans' Illnesses
- Conditions
- Persian Gulf SyndromeMycoplasma Infections
- First Posted Date
- 2001-01-01
- Last Posted Date
- 2023-10-30
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 450
- Registration Number
- NCT00007735
- Locations
- 🇺🇸
Vamc - Durham, Nc, Durham, North Carolina, United States
🇺🇸Vamc - Nashville, Tn, Nashville, Tennessee, United States
🇺🇸Vamc - Houston, Tx, Houston, Texas, United States
Doxycycline and OA Progression
- Conditions
- Osteoarthritis
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2013-04-30
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 432
- Registration Number
- NCT00000403
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸University of Arizona Arthritis Center, Tucson, Arizona, United States
🇺🇸University of Alabama at Birmingham, Birmingham, Alabama, United States
Drug Development Updates
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