Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
Lipidome and Microbiome Profile of Acne
- First Posted Date
- 2016-03-21
- Last Posted Date
- 2024-01-02
- Lead Sponsor
- University of California, Davis
- Target Recruit Count
- 30
- Registration Number
- NCT02713607
- Locations
- 🇺🇸
UC Davis Dept of Dermatology, Sacramento, California, United States
Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?
- First Posted Date
- 2016-02-23
- Last Posted Date
- 2016-02-23
- Lead Sponsor
- Rothman Institute Orthopaedics
- Registration Number
- NCT02688738
Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis
- First Posted Date
- 2015-12-08
- Last Posted Date
- 2019-08-07
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 3
- Registration Number
- NCT02623959
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
A Two Week Nitazoxanidebased Quadruple Regimen
- Conditions
- Interventions
- First Posted Date
- 2015-12-03
- Last Posted Date
- 2018-01-03
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 100
- Registration Number
- NCT02621359
- Locations
- 🇪🇬
Tropical medicine dept.-Tanta university hospital, Tanta, Egypt
Trial of Antimicrobials Versus Placebo in Addition to Fecal Transplant Therapy in Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2015-11-17
- Last Posted Date
- 2021-02-10
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 75
- Registration Number
- NCT02606032
- Locations
- 🇨🇦
Hamilton Health Sciences / McMaster University, Hamilton, Ontario, Canada
Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps
- Conditions
- Interventions
- First Posted Date
- 2015-10-06
- Last Posted Date
- 2018-01-09
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 49
- Registration Number
- NCT02569437
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.
- Conditions
- Interventions
- First Posted Date
- 2015-09-30
- Last Posted Date
- 2021-05-13
- Target Recruit Count
- 103
- Registration Number
- NCT02564471
- Locations
- 🇺🇸
State University of New York, Upstate Medical University (SUNY-UMU), Syracuse, New York, United States
Changes in Myocardial Biomechanics and Early Short-term Doxycycline Therapy in Patients With Primary Anterior STEMI
- Conditions
- Interventions
- First Posted Date
- 2015-09-29
- Last Posted Date
- 2016-12-13
- Lead Sponsor
- Russian Academy of Medical Sciences
- Target Recruit Count
- 45
- Registration Number
- NCT02562651
- Locations
- 🇷🇺
Research Institutite for Cardiology, Tomsk, Tomskii region, Russian Federation
Six Versus Two Weeks Treatment With Doxycycline in Lyme Neuroborreliosis
- Conditions
- Interventions
- First Posted Date
- 2015-09-17
- Last Posted Date
- 2024-01-23
- Lead Sponsor
- Sorlandet Hospital HF
- Target Recruit Count
- 121
- Registration Number
- NCT02553473
Tick-borne Encephalitis and Positive Borrelial Antibodies
- Conditions
- Interventions
- First Posted Date
- 2015-06-04
- Last Posted Date
- 2018-10-16
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 100
- Registration Number
- NCT02463942
- Locations
- 🇸🇮
UMC Ljubljana, Department of Infectious Diseases, Ljubljana, Slovenia
Drug Development Updates
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