MedPath

MF59 Adjuvant

Generic Name
MF59 Adjuvant

Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian Influenza

Phase 2
Completed
Conditions
Avian Influenza
Influenza Immunisation
Interventions
Biological: A/H7N9
Other: Phosphate Buffered Saline (PBS) diluent
First Posted Date
2018-09-24
Last Posted Date
2021-05-17
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
372
Registration Number
NCT03682120
Locations
🇺🇸

Baylor College of Medicine - Molecular Virology and Microbiology, Houston, Texas, United States

🇺🇸

Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases, Seattle, Washington, United States

🇺🇸

University of Alabama at Birmingham School of Medicine - Alabama Vaccine Research Clinic, Birmingham, Alabama, United States

and more 4 locations

H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults: Immunology

Phase 1
Completed
Conditions
Avian Influenza
Interventions
Biological: Monovalent Influenza A/H5N8 vaccine
First Posted Date
2017-01-09
Last Posted Date
2024-07-05
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
388
Registration Number
NCT03014310
Locations
🇺🇸

Duke Vaccine and Trials Unit, Durham, North Carolina, United States

🇺🇸

The University of Texas Medical Branch - Sealy Center for Vaccine Development (SCVD), Galveston, Texas, United States

🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

and more 4 locations

H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults

Phase 1
Completed
Conditions
Avian Influenza
Influenza
Interventions
Biological: Monovalent Influenza A/H5N8 vaccine
First Posted Date
2015-12-08
Last Posted Date
2019-10-23
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
276
Registration Number
NCT02624219
Locations
🇺🇸

University of Iowa - Vaccine Research and Education Unit, Iowa City, Iowa, United States

🇺🇸

Saint Louis University - Center for Vaccine Development, Saint Louis, Missouri, United States

🇺🇸

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati, Ohio, United States

and more 1 locations

A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine

Phase 1
Completed
Conditions
Avian Influenza
Immunisation
Interventions
Biological: Influenza Virus Vaccine, Live Attenuated H7N9 Anhui 2013/AA ca
Biological: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
First Posted Date
2014-09-29
Last Posted Date
2020-01-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
62
Registration Number
NCT02251288
Locations
🇺🇸

University of Rochester Medical Center - Vaccine Research Unit, Rochester, New York, United States

H7N9 Mix and Match With MF59 in Healthy Elderly Persons

Phase 2
Completed
Conditions
Avian Influenza
Interventions
Biological: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
First Posted Date
2014-08-11
Last Posted Date
2017-07-06
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
479
Registration Number
NCT02213354
Locations
🇺🇸

University of Iowa - Vaccine Research and Education Unit, Iowa City, Iowa, United States

🇺🇸

Saint Louis University - Center for Vaccine Development, Saint Louis, Missouri, United States

🇺🇸

Emory Vaccine Center - The Hope Clinic, Decatur, Georgia, United States

and more 7 locations

H7N9 Mix and Match With AS03 and MF59 in Healthy Adults

Phase 2
Completed
Conditions
Influenza
Interventions
Biological: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
First Posted Date
2013-09-13
Last Posted Date
2017-07-06
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
980
Registration Number
NCT01942265
Locations
🇺🇸

Saint Louis University - Center for Vaccine Development, Saint Louis, Missouri, United States

🇺🇸

University of Maryland School of Medicine - Center for Vaccine Development - Baltimore, Baltimore, Maryland, United States

🇺🇸

Vanderbilt University Medical Center - Infectious Diseases, Nashville, Tennessee, United States

and more 2 locations

H7N9 Mix and Match With MF59 in Healthy Adults

Phase 2
Completed
Conditions
Influenza
Interventions
Biological: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
First Posted Date
2013-09-10
Last Posted Date
2016-12-12
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
700
Registration Number
NCT01938742
Locations
🇺🇸

Emory Vaccine Center - The Hope Clinic, Decatur, Georgia, United States

🇺🇸

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati, Ohio, United States

🇺🇸

University of Texas Medical Branch - Pediatrics - Infectious Diseases and Immunology - Galveston, Galveston, Texas, United States

and more 1 locations

H5N1 Mix and Match With MF59

Phase 1
Completed
Conditions
Influenza
Interventions
Other: Phosphate Buffered Saline (PBS) diluent
Biological: H5N1 Antigen
First Posted Date
2011-03-17
Last Posted Date
2013-01-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
270
Registration Number
NCT01317745
Locations
🇺🇸

University of Iowa - Infectious Disease Clinic, Iowa City, Iowa, United States

🇺🇸

Emory Children's Center - Division of Pediatric Infectious Diseases, Atlanta, Georgia, United States

🇺🇸

Emory Vaccine Center - The Hope Clinic, Decatur, Georgia, United States

and more 2 locations

Inactivated Influenza A/H9N2 Vaccine With and Without MF59 Adjuvant in Ambulatory Adults

Phase 1
Completed
Conditions
Influenza
Interventions
Biological: Influenza A/H9N2 vaccine
First Posted Date
2005-08-23
Last Posted Date
2010-08-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
96
Registration Number
NCT00133471
Locations
🇺🇸

Baylor College of Medicine, Houston, Texas, United States

Recombinant CMV gB Vaccine in Postpartum Women

Phase 2
Completed
Conditions
Cytomegalovirus Infections
Interventions
Biological: CMV gB vaccine
Drug: Placebo
First Posted Date
2005-08-01
Last Posted Date
2011-09-20
Lead Sponsor
Robert Pass, MD
Target Recruit Count
464
Registration Number
NCT00125502
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

University of Alabama at Tuscaloosa, Tuscaloosa, Alabama, United States

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