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Acenocoumarol

Generic Name
Acenocoumarol
Drug Type
Small Molecule
Chemical Formula
C19H15NO6
CAS Number
152-72-7
Unique Ingredient Identifier
I6WP63U32H

Overview

Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood.

Background

Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood.

Indication

For the treatment and prevention of thromboembolic diseases. More specifically, it is indicated for the prevention of cerebral embolism, deep vein thrombosis, pulmonary embolism, thromboembolism in infarction and transient ischemic attacks. It is used for the treatment of deep vein thrombosis and myocardial infarction.

Associated Conditions

  • Coronary Occlusions
  • Pulmonary Embolism
  • Systemic Embolism
  • Transient Ischemic Attack
  • Venous Thrombosis (Disorder)

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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