Chlorzoxazone

Generic Name
Chlorzoxazone
Brand Names
Lorzone, Parafon Forte
Drug Type
Small Molecule
Chemical Formula
C7H4ClNO2
CAS Number
95-25-0
Unique Ingredient Identifier
H0DE420U8G
Background

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

Indication

For the relief of discomfort associated with acute painful musculoskeletal conditions.

Associated Conditions
Acute painful musculoskeletal conditions
Associated Therapies
-

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

First Posted Date
2017-04-06
Last Posted Date
2017-08-10
Lead Sponsor
Swedish Orphan Biovitrum
Target Recruit Count
36
Registration Number
NCT03103568
Locations
🇩🇪

PAREXEL EPCU Berlin, Berlin, Germany

Chlorzoxazone in Hip and Knee Arthroplasty

First Posted Date
2015-04-01
Last Posted Date
2019-09-09
Lead Sponsor
Northern Orthopaedic Division, Denmark
Target Recruit Count
400
Registration Number
NCT02405104
Locations
🇩🇰

Northern Orthopaedic Division, Clinic Farsø, Aalborg University Hospital, Farsø, Northern Jutland, Denmark

The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine Surgery

First Posted Date
2013-09-02
Last Posted Date
2015-09-17
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
110
Registration Number
NCT01933542
Locations
🇩🇰

Glostrup University Hospital, Glostrup, Denmark

Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-04-27
Last Posted Date
2020-11-20
Lead Sponsor
University of California, San Francisco
Target Recruit Count
48
Registration Number
NCT01342341
Locations
🇺🇸

Ernest Gallo Clinic and Research Center, Emeryville, California, United States

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