Indocyanine green acid form
- Generic Name
- Indocyanine green acid form
- Brand Names
- Ic-green
- Drug Type
- Small Molecule
- Chemical Formula
- C43H48N2O6S2
- CAS Number
- 28782-33-4
- Unique Ingredient Identifier
- C4V974V932
- Background
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
- Indication
For Determining Cardiac Output, Hepatic Function and Liver Blood Flow
For ophthalmic angiography
- Associated Conditions
- -
- Associated Therapies
- -
Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque
- Conditions
- AtherosclerosisAtherosclerotic PlaqueCarotid Stenosis
- Interventions
- First Posted Date
- 2013-06-10
- Last Posted Date
- 2017-02-02
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 5
- Registration Number
- NCT01873716
- Locations
- πΊπΈ
Massachusetts General Hospital, Boston, Massachusetts, United States
Intraoperative Imaging of Breast Cancer With Indocyanine Green
- Conditions
- Invasive Lobular CarcinomaDuctal CarcinomaInvasive Ductal Carcinoma
- Interventions
- First Posted Date
- 2013-02-21
- Last Posted Date
- 2021-01-28
- Lead Sponsor
- Abramson Cancer Center at Penn Medicine
- Target Recruit Count
- 10
- Registration Number
- NCT01796041
- Locations
- πΊπΈ
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer
- Conditions
- Breast Cancer
- Interventions
- Device: SPY Elite ImagingDrug: Indocyanine GreenDrug: Isosulfan blueDrug: 99technetium-sulfur colloid radiolabel
- First Posted Date
- 2013-01-18
- Last Posted Date
- 2017-12-11
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 23
- Registration Number
- NCT01771666
- Locations
- πΊπΈ
Stanford University, School of Medicine, Stanford, California, United States
Lymphatic Mapping for Sentinel Node Identification and Analysis
- First Posted Date
- 2012-08-10
- Last Posted Date
- 2019-08-09
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 30
- Registration Number
- NCT01662752
- Locations
- π¬π§
North West London Hospital, London, UK, United Kingdom
Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green
- First Posted Date
- 2011-04-14
- Last Posted Date
- 2018-02-05
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 10
- Registration Number
- NCT01335893
- Locations
- πΊπΈ
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors
- Conditions
- Stage I Renal Cell CancerStage II Renal Cell CancerRecurrent Renal Cell Cancer
- Interventions
- First Posted Date
- 2011-01-24
- Last Posted Date
- 2017-10-13
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 28
- Registration Number
- NCT01281488
- Locations
- πΊπΈ
City of Hope Medical Center, Duarte, California, United States
Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract
- Conditions
- Colorectal PolypsDistal Colonic LesionsHigh Risk Polyposis Syndrome
- Interventions
- First Posted Date
- 2010-04-28
- Last Posted Date
- 2014-02-24
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 4
- Registration Number
- NCT01112514
- Locations
- πΊπΈ
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
πΊπΈMassachusetts General Hospital, Boston, Massachusetts, United States
Advanced Gastrointestinal Endoscopic Imaging
- Conditions
- Gastrointestinal DiseasesGastrointestinal Stromal Tumor (GIST)Gastric (Stomach) Cancer
- Interventions
- Device: Dual axis endoscopic microscopeDevice: wide field fluorescence systemDevice: CellVizioDrug: fluorescent PeptideDrug: fluoresceinDrug: indocyanine green
- First Posted Date
- 2009-12-17
- Last Posted Date
- 2024-06-26
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 3
- Registration Number
- NCT01034670
- Locations
- πΊπΈ
Stanford University School of Medicine, Stanford, California, United States
Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction
- Conditions
- Unspecified Adult Solid Tumor, Protocol SpecificLung Cancer
- Interventions
- Drug: indocyanine greenDrug: lidocaineDrug: vinorelbine ditartrateOther: high performance liquid chromatographyOther: intracellular fluorescence polarization analysisOther: liquid chromatographyOther: mass spectrometryOther: pharmacological study
- First Posted Date
- 2007-10-08
- Last Posted Date
- 2019-03-11
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 47
- Registration Number
- NCT00540982
- Locations
- πΊπΈ
City of Hope Medical Group, Pasadena, California, United States
πΊπΈCity of Hope Comprehensive Cancer Center, Duarte, California, United States
Insulin on Post Burn Hypermetabolism
- Conditions
- Burns
- Interventions
- First Posted Date
- 2005-08-29
- Last Posted Date
- 2012-04-12
- Lead Sponsor
- United States Army Institute of Surgical Research
- Target Recruit Count
- 14
- Registration Number
- NCT00137254
- Locations
- πΊπΈ
US Army Institute of Surgical Research, Fort Sam Houston, Texas, United States
Drug Development Updates
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