Terbutaline

Generic Name
Terbutaline
Brand Names
Bricanyl
Drug Type
Small Molecule
Chemical Formula
C12H19NO3
CAS Number
23031-25-6
Unique Ingredient Identifier
N8ONU3L3PG
Background

Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.

Terbutaline was granted FDA approval on 25 March 1974.

Indication

Terbutaline is indicated for prevention and reversal of bronchospasm in patients at least 12 years old, with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Associated Conditions
Asthma, Bronchospasm, Chronic Cough (CC), Chronic Obstructive Pulmonary Disease (COPD), Cough, Premature Labour, Productive cough
Associated Therapies
Airway secretion clearance therapy

Comparing the Efficacy of Bricanyl M2 and Bricanyl M3 at 0.5 and 1.5 mg Dose Levels, to Allow for a Switch From Bricanyl Turbuhaler M2 to Bricanyl Turbuhaler M3

First Posted Date
2014-12-23
Last Posted Date
2017-01-13
Lead Sponsor
AstraZeneca
Target Recruit Count
95
Registration Number
NCT02322788
Locations
🇸🇪

Research Site, Lund, Sweden

β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation

First Posted Date
2013-09-17
Last Posted Date
2018-01-26
Lead Sponsor
University of Monastir
Target Recruit Count
250
Registration Number
NCT01944033
Locations
🇹🇳

University Hospital of Monastir, Monastir,, Monastir, Tunisia

🇹🇳

Fattouma Bourguiba University Hospital, Monastir, Tunisia

Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement

First Posted Date
2012-07-27
Last Posted Date
2015-01-19
Lead Sponsor
Kai Schoenhage
Target Recruit Count
250
Registration Number
NCT01651962
Locations
🇺🇸

University of Arizona Medical Center, Tucson, Arizona, United States

🇺🇸

Tucson Medical Center, Tucson, Arizona, United States

Comparing Symbicort® As-Needed or Bricanyl As-Needed or Pulmicort® Once Daily + Bricanyl As-Needed in Asthma Patients

First Posted Date
2009-10-06
Last Posted Date
2012-08-14
Lead Sponsor
AstraZeneca
Target Recruit Count
66
Registration Number
NCT00989833
Locations
🇸🇪

Research Site, Uppsala, Sweden

Use of Terbutaline or a Reduction in Basal Insulin in the Prevention of Nocturnal Hypoglycemia

First Posted Date
2009-09-10
Last Posted Date
2013-10-11
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
16
Registration Number
NCT00974051
Locations
🇺🇸

Barbara Davis Center, Aurora, Colorado, United States

Prn Budesonide/Formoterol Versus Regular Budesonide/Formoterol Plus Prn Terbutaline in Mild-Moderate Asthma

First Posted Date
2009-02-23
Last Posted Date
2014-05-30
Lead Sponsor
Università degli Studi di Ferrara
Target Recruit Count
860
Registration Number
NCT00849095
Locations
🇮🇹

Ospedale regionale Umberto I, Unità Operativa di Allergologia, Ancona, AN, Italy

🇮🇹

Fondazione S. Maugeri - IRCCS -dipartimento di Pneumologia riabilitativa, Cassano delle Murge, BA, Italy

🇮🇹

Giuseppina Bertorelli, Parma, Italy

and more 28 locations

A Pilot Study to Evaluate the Safety of Terbutaline in Children With Type 1 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-02-05
Last Posted Date
2016-09-05
Lead Sponsor
Jaeb Center for Health Research
Target Recruit Count
9
Registration Number
NCT00607503
Locations
🇺🇸

Division of Pediatric Endocrinology and Diabetes, Stanford University, Stanford, California, United States

🇺🇸

Jaeb Center for Health Research, Tampa, Florida, United States

🇺🇸

Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States

and more 3 locations

SHARE - Symbicort and Health Economics in a Real Life Evaluation

Phase 3
Completed
Conditions
First Posted Date
2005-12-01
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
1970
Registration Number
NCT00259766
Locations
🇸🇪

Reseearch Site, Perstorp, Sweden

🇸🇪

Research Site, Örebro, Sweden

🇸🇪

Research site, Ödeshög, Sweden

Nitroglycerin Versus Terbutaline for Intrapartum Fetal Resuscitation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2005-09-16
Last Posted Date
2011-03-08
Lead Sponsor
Stanford University
Target Recruit Count
110
Registration Number
NCT00185887
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Trial of Terbutaline for the Treatment of Status Asthmaticus in Children

Phase 4
Completed
Conditions
First Posted Date
2005-07-29
Last Posted Date
2013-02-15
Lead Sponsor
Connecticut Children's Medical Center
Target Recruit Count
40
Registration Number
NCT00124995
Locations
🇺🇸

CT Children's Medical Center, Hartford, Connecticut, United States

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