Triptorelin
- Generic Name
- Triptorelin
- Brand Names
- Decapeptyl, Trelstar, Triptodur
- Drug Type
- Small Molecule
- Chemical Formula
- C64H82N18O13
- CAS Number
- 57773-63-4
- Unique Ingredient Identifier
- 9081Y98W2V
- Background
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men.
- Indication
Triptorelin is indicated for the palliative treatment of advanced prostate cancer.
- Associated Conditions
- Advanced Prostate Cancer
- Associated Therapies
- Controlled ovarian hyperstimulation therapy
Follicle Size and Oocyte Development
- Conditions
- IVF Treatment
- Interventions
- Diagnostic Test: Follicle measurment
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2022-06-24
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT03660813
- Locations
- 🇮🇱
Sheba Medical Center, Ramat Gan, Israel
Efficacy and Safety of GnRH Analogue Triptorelin for HIV-1 Reservoir Reduction in ART Treated HIV-1 Infected Patients
- First Posted Date
- 2018-05-24
- Last Posted Date
- 2021-01-13
- Lead Sponsor
- Immune System Regulation AB
- Target Recruit Count
- 52
- Registration Number
- NCT03536234
- Locations
- 🇩🇪
Zentrum für Infektiologie Berlin Prenzlauer Berg, Berlin, Germany
🇸🇪Södersjukhuset, Stockholm, Sweden
🇩🇪MVZ Karlsplatz, Munich, Germany
Early Preparation With Gonadotropin- Releasing Hormon (GnRh) Agonists Injection With Frozen-Thawed Embryo Transfer?
- First Posted Date
- 2017-11-27
- Last Posted Date
- 2017-11-27
- Lead Sponsor
- Benha University
- Target Recruit Count
- 200
- Registration Number
- NCT03353883
- Locations
- 🇪🇬
Benha university hospital, Banhā, Qaluibia, Egypt
Study to Compare the Oestradiol Suppression, Clinical Efficacy and Safety of Two Formulations of Triptorelin (Triptorelin Pamoate PR 3-month and Triptorelin Acetate PR 1-month) in Chinese Subjects With Endometriosis
- Conditions
- Endometriosis
- Interventions
- First Posted Date
- 2017-07-27
- Last Posted Date
- 2021-10-14
- Lead Sponsor
- Ipsen
- Target Recruit Count
- 300
- Registration Number
- NCT03232281
- Locations
- 🇨🇳
Chinese PLA General Hospital, Beijing, China
🇨🇳Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
🇨🇳The First Affiliated Hospital of Dalian Medical University, Dalian, China
Single Dose Recombinant Human Follicle Stimulating Hormone Fc Husion Protein (KN015) in Healthy Volunteers
- First Posted Date
- 2017-06-20
- Last Posted Date
- 2017-06-20
- Lead Sponsor
- Alphamab Jilin Co., Ltd.
- Target Recruit Count
- 50
- Registration Number
- NCT03192527
- Locations
- 🇨🇳
The First Hospital of Jilin University, Chuangchun, Jilin, China
The Use of GnRH Agonist Trigger for Final Follicle Maturation in Women Undergoing Assisted Reproductive Technologies
- First Posted Date
- 2017-05-30
- Last Posted Date
- 2023-07-20
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 277
- Registration Number
- NCT03169166
- Locations
- 🇱🇧
American University of Beirut Medical Center, Beirut, Lebanon
Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI
- Conditions
- Invitro Fertilization
- Interventions
- First Posted Date
- 2017-04-18
- Last Posted Date
- 2017-11-07
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 204
- Registration Number
- NCT03118830
- Locations
- 🇪🇬
Ahmed Maged, Cairo, Egypt
Luteal Phase Support in Insemination Cycles
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- Tampere University Hospital
- Target Recruit Count
- 167
- Registration Number
- NCT03115307
- Locations
- 🇫🇮
Tampere University Hospital, Tampere, Finland
Clinical Study of Recombinant Human Follitropin for Injection Assisted in COH Assisted IVF-ET
- Conditions
- Ovarian Hyperstimulation Syndrome
- Interventions
- First Posted Date
- 2017-03-06
- Last Posted Date
- 2017-03-06
- Lead Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
- Target Recruit Count
- 252
- Registration Number
- NCT03071172
- Locations
- 🇨🇳
Sun Yat-sen Memorial Hospital, Guangzhou, Guangdong, China
🇨🇳Peking University Third Hospital, Beijing, China
🇨🇳The first Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
GNRH Agonist Trigger and Modified Luteal Phase Adding a Bolus of GnRHa at the Time of Implantation: a RCT
- First Posted Date
- 2017-02-01
- Last Posted Date
- 2017-07-07
- Lead Sponsor
- Centre Hospitalier Universitaire Ibn Rochd
- Target Recruit Count
- 328
- Registration Number
- NCT03039049
- Locations
- 🇩🇿
Ibnrochd IVF center, Constantine, Algeria
🇩🇿Ibnrochd Clinic, Constantine, Algeria
Drug Development Updates
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