MedPath

Cetrorelix

Generic Name
Cetrorelix
Brand Names
Cetrotide
Drug Type
Small Molecule
Chemical Formula
C70H92ClN17O14
CAS Number
120287-85-6
Unique Ingredient Identifier
OON1HFZ4BA
Background

Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. Cetrorelix does not allow the premature release of these eggs to occur.

Indication

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation

Associated Therapies
Controlled Ovarian Stimulation

PPOS Protocol Versus GnRH Anatagonist for Expected Normal Responder Patients Undergoing ART : a Randomized Clinical Trial

Phase 3
Completed
Conditions
PPOS
GnRH Antagonist
Assisted Reproductive Techniques
Interventions
First Posted Date
2025-03-11
Last Posted Date
2025-03-11
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
328
Registration Number
NCT06868576
Locations
🇪🇬

Ciro University Kasr Alainy OBGYN Hospital, Cairo, Alquahira, Egypt

Can Drospirenone be Used to Prevent LH Surge in Controlled Ovarian Stimulation in PCOS?!

Phase 1
Completed
Conditions
PCOS (Polycystic Ovary Syndrome)
Interventions
First Posted Date
2024-09-23
Last Posted Date
2025-01-22
Lead Sponsor
Ahmed Saad
Target Recruit Count
50
Registration Number
NCT06608186
Locations
🇪🇬

Hawaa Fertility center, Banhā, Qalyubiya, Egypt

PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study)

Not Applicable
Recruiting
Conditions
Progestins Primed Ovarian Stimulation
Interventions
First Posted Date
2024-04-22
Last Posted Date
2024-04-26
Lead Sponsor
Mỹ Đức Hospital
Target Recruit Count
626
Registration Number
NCT06378268
Locations
🇻🇳

My Duc Hospital, Ho Chi Minh City, Vietnam

Effectiveness of Generic Versus Reference Cetrorelix Acetate for Ovarian Stimulation Using a Gonadotropin-releasing Hormone(GnRH)Antagonist Protocol in Women Undergoing IVF

Not Applicable
Recruiting
Conditions
Infertility
Interventions
First Posted Date
2023-09-05
Last Posted Date
2024-07-10
Lead Sponsor
Northwest Women's and Children's Hospital, Xi'an, Shaanxi
Target Recruit Count
1338
Registration Number
NCT06023602
Locations
🇨🇳

He Cai, Xi'an, None Selected, China

Dydrogesterone, Cetrorelix Acetate and Triptorelin in Intra Cytoplasmic Sperm Injection Outcomes

Phase 3
Recruiting
Conditions
IVF
Interventions
First Posted Date
2023-08-02
Last Posted Date
2023-08-02
Lead Sponsor
Beni-Suef University
Target Recruit Count
387
Registration Number
NCT05972902
Locations
🇪🇬

Beni-suef university Hospital, Banī Suwayf, Beni Suef, Egypt

Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist in With Expected High Ovarian Response Undergoing in Vitro Fertilization

Phase 2
Not yet recruiting
Conditions
IVF
PCO
Interventions
First Posted Date
2023-07-19
Last Posted Date
2023-08-03
Lead Sponsor
Beni-Suef University
Target Recruit Count
200
Registration Number
NCT05951400
Locations
🇪🇬

Beni-suef university Hospital, Banī Suwayf, Beni Suef, Egypt

Dydrogesterone-Primed Ovarian Stimulation Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in ICSI

Not Applicable
Recruiting
Conditions
Fertility Issues
Ovary Cyst
Interventions
Other: progestin primed ovarian stimulation protocol
First Posted Date
2023-03-02
Last Posted Date
2023-03-02
Lead Sponsor
Zagazig University
Target Recruit Count
79
Registration Number
NCT05751681
Locations
🇪🇬

Zagazig University, Zagazig, Egypt

Efficacy and Safety of BG2109 During Controlled Ovarian Hyperstimulation in Female Subjects Undergoing ART Procedures

Phase 2
Not yet recruiting
Conditions
Assisted Reproductive Technology
Controlled Ovarian Hyperstimulation
Interventions
First Posted Date
2023-02-22
Last Posted Date
2023-07-27
Lead Sponsor
Bio Genuine (Shanghai) Biotech Co., Ltd.
Target Recruit Count
240
Registration Number
NCT05738382
Locations
🇨🇳

Site No3, Wuhan, China

🇨🇳

Site No7, Guangzhou, China

🇨🇳

Site No9, Haikou, China

and more 7 locations

Progestin-primed Ovarian Stimulation Protocol Versus GnRH Antagonist Protocol in Polycystic Ovary Syndrome Patients Undergoing IVF/ICSI Cycles

First Posted Date
2021-11-09
Last Posted Date
2021-11-09
Lead Sponsor
Mansoura University
Target Recruit Count
200
Registration Number
NCT05112692

GnRH Antagonist Pre-treatment in the Early Follicular Phase for Resolution of a Baseline Functional Ovarian Cyst

Phase 4
Conditions
IVF
Ovarian Cysts
Interventions
First Posted Date
2021-08-06
Last Posted Date
2021-10-13
Lead Sponsor
Assaf-Harofeh Medical Center
Target Recruit Count
15
Registration Number
NCT04993924
Locations
🇮🇱

Shamir Medical center, Be'er Ya'aqov, Israel

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