Desloratadine
- Generic Name
- Desloratadine
- Brand Names
- Aerius, Clarinex, Clarinex-D, Neoclarityn, Desloratadine ratiopharm, Desloratadine Teva, Desloratadine Actavis, Dasselta, Azomyr
- Drug Type
- Small Molecule
- Chemical Formula
- C19H19ClN2
- CAS Number
- 100643-71-8
- Unique Ingredient Identifier
- FVF865388R
- Background
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
- Indication
For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
- Associated Conditions
- Allergic Rhinitis (AR), Asthma, Chronic Idiopathic Urticaria, Common Cold, Nasal Congestion, Perennial Allergic Rhinitis (PAR), Seasonal Allergic Rhinitis, Nasal symptoms, Non-nasal symptoms
- Associated Therapies
- Antihistamine
Desloratadine 5, 10 and 20mg in Patients With Cold Urticaria
- First Posted Date
- 2011-09-30
- Last Posted Date
- 2011-10-03
- Lead Sponsor
- Marcus Maurer
- Target Recruit Count
- 30
- Registration Number
- NCT01444196
- Locations
- 🇩🇪
Department of Dermatology, Venerology and Allergology, Berlin, Germany
Investigate the Safety/Tolerability and Efficacy of Bilastine 20mg in Korean Patients With Seasonal Allergic Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2011-07-22
- Last Posted Date
- 2014-07-10
- Lead Sponsor
- Yuhan Corporation
- Target Recruit Count
- 239
- Registration Number
- NCT01400828
- Locations
- 🇰🇷
Yonsei University college of Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of
Bioavailability Study of Desloratadine 5 mg Tablet of Dr. Reddy's Under Fed Conditions
- First Posted Date
- 2011-03-14
- Last Posted Date
- 2011-06-08
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 28
- Registration Number
- NCT01314352
- Locations
- 🇺🇸
SFBC, Ft. Myers, Inc.,, Ft. Myers, Florida, United States
Bioavailability Study of Dr. Reddy's Desloratadine Tablets, 5 mg Under Fasting Conditions.
- First Posted Date
- 2011-03-14
- Last Posted Date
- 2012-02-20
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 28
- Registration Number
- NCT01314339
- Locations
- 🇺🇸
SFBC, Ft. Myers, Inc.,, Ft. Myers, Florida, United States
A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
- Conditions
- Interventions
- First Posted Date
- 2010-04-22
- Last Posted Date
- 2012-04-05
- Lead Sponsor
- Faes Farma, S.A.
- Target Recruit Count
- 720
- Registration Number
- NCT01108783
Comparison of the Effects of Desloratadine and Placebo in the Relief of Nasal Symptom Scores in Subjects With Seasonal Allergic Rhinitis to Cypress Pollen (Study P02836)
- First Posted Date
- 2009-03-23
- Last Posted Date
- 2024-08-15
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 233
- Registration Number
- NCT00867191
Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Allergic Skin Inflammation (P03475)
- First Posted Date
- 2009-01-06
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 40
- Registration Number
- NCT00817076
Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Hayfever With or Without Asthma (P03472)
- First Posted Date
- 2008-12-09
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 54
- Registration Number
- NCT00805324
Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)
- First Posted Date
- 2008-12-09
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 311
- Registration Number
- NCT00805584
How Desloratadine (Clarinex, Aerius) Affects Quality of Life in Patients With Chronic Idiopathic Urticaria (Have Had Hives for 6 Weeks or Longer)(Study P02988)
- First Posted Date
- 2008-11-21
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 282
- Registration Number
- NCT00795158
Drug Development Updates
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