Milnacipran

Generic Name
Milnacipran
Brand Names
Savella
Drug Type
Small Molecule
Chemical Formula
C15H22N2O
CAS Number
92623-85-3
Unique Ingredient Identifier
G56VK1HF36
Background

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression . Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of treating fibromyalgia , although other regional ...

Indication

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for the management of fibromyalgia in patients that are 18 years old or above .
...

Associated Conditions
Fibromyalgia
Associated Therapies
-

Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2008-11-19
Last Posted Date
2010-07-01
Lead Sponsor
Forest Laboratories
Target Recruit Count
2
Registration Number
NCT00793520
Locations
🇺🇸

Forest Investigative Site, Ann Arbor, Michigan, United States

FMS European Long-Term Study

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-09-23
Last Posted Date
2013-07-11
Lead Sponsor
Pierre Fabre Medicament
Target Recruit Count
490
Registration Number
NCT00757731
Locations
🇷🇴

Dr I CANTACUZINO CLINICAL HOSPITAL, Bucharest, Romania

🇨🇿

Rheumatology Ambulance, Pardubice, Czech Republic

🇫🇮

Kuopion Oma Laakari Oy, Kuopio, Finland

and more 7 locations

Evaluation of the Antinociceptive and Analgesic Effects of Milnacipran

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-09-23
Last Posted Date
2013-07-11
Lead Sponsor
Pierre Fabre Medicament
Target Recruit Count
153
Registration Number
NCT00757679
Locations
🇨🇭

Clinical Pharmacology & Toxicology Multidisciplinary Pain Centre, Geneve, Switzerland

Dose Milnacipran Prevent Depressive Symptoms in Patients With Acute Stroke?

Not Applicable
Conditions
Interventions
First Posted Date
2008-02-01
Last Posted Date
2008-10-17
Lead Sponsor
Chang Gung Memorial Hospital
Target Recruit Count
120
Registration Number
NCT00606203
Locations
🇨🇳

Chang Gung Memorial Hospital, Chiayi, Taiwan

A Multicentre Trial to Determine the Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia Syndrome

Phase 3
Completed
Conditions
Interventions
First Posted Date
2007-02-16
Last Posted Date
2013-07-11
Lead Sponsor
Pierre Fabre Medicament
Target Recruit Count
1429
Registration Number
NCT00436033
Locations
🇨🇿

Rheumatology Ambulance, Pardubice, Czech Republic

🇩🇰

FREDERIKSBERG HOSPITAL - Clinic of Rheumatology, Frederiksberg, Denmark

🇮🇹

Ospedale Luigi Sacco, Milano, Italy

and more 10 locations

Study Evaluating Effexor XR for Major Depression.

Phase 3
Completed
Conditions
First Posted Date
2005-09-23
Last Posted Date
2007-05-24
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
590
Registration Number
NCT00225511
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