Milnacipran

Generic Name
Milnacipran
Brand Names
Savella
Drug Type
Small Molecule
Chemical Formula
C15H22N2O
CAS Number
92623-85-3
Unique Ingredient Identifier
G56VK1HF36
Background

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression . Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of treating fibromyalgia , although other regional ...

Indication

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for the management of fibromyalgia in patients that are 18 years old or above .
...

Associated Conditions
Fibromyalgia
Associated Therapies
-

Effect of Milnacipran / Gabapentin in Fibromyalgia

First Posted Date
2022-05-20
Last Posted Date
2022-05-20
Lead Sponsor
Mansoura University
Target Recruit Count
75
Registration Number
NCT05384210
Locations
🇪🇬

Mansoura University, Mansoura, DK, Egypt

Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2016-05-26
Last Posted Date
2022-11-04
Lead Sponsor
University Hospital, Lille
Target Recruit Count
80
Registration Number
NCT02783430
Locations
🇫🇷

Chu Amiens Picardie, Amiens, France

🇫🇷

Ch Calais, Calais, France

🇫🇷

Maison Medicale Jean Xxiii - Lille, Lille, France

and more 6 locations

Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With Sciatica

First Posted Date
2013-08-01
Last Posted Date
2019-04-02
Lead Sponsor
Rambam Health Care Campus
Target Recruit Count
150
Registration Number
NCT01914042
Locations
🇮🇱

Rambam Health Care Campus, Haifa, Israel

Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial

Phase 3
Completed
Conditions
Interventions
First Posted Date
2013-04-11
Last Posted Date
2023-10-26
Lead Sponsor
Duke University
Target Recruit Count
26
Registration Number
NCT01829243
Locations
🇺🇸

Duke University Medical Center / Civitan Building, Durham, North Carolina, United States

Milnacipran for Lumbosacral Radicular Pain

First Posted Date
2013-01-29
Last Posted Date
2014-07-23
Lead Sponsor
Duke University
Target Recruit Count
13
Registration Number
NCT01777581

Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of the Pain on the Efficacy of Milnacipran in Fibromyalgia Therapy

Phase 2
Conditions
Interventions
First Posted Date
2012-12-11
Last Posted Date
2014-07-08
Lead Sponsor
University Hospital, Clermont-Ferrand
Target Recruit Count
48
Registration Number
NCT01747044
Locations
🇫🇷

CHU de Clermont-Ferrand, Clermont-Ferrand, France

Milnacipran for Chronic Pain in Knee Osteoarthritis

First Posted Date
2012-01-16
Last Posted Date
2015-06-22
Lead Sponsor
Dr. Norman Harden
Target Recruit Count
46
Registration Number
NCT01510457

Milnacipran (Savella) in Irritable Bowel Syndrome (IBS)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2011-11-16
Last Posted Date
2017-04-13
Lead Sponsor
Spencer Dorn, MD, MPH
Target Recruit Count
2
Registration Number
NCT01471379
Locations
🇺🇸

UNC Center for Functional GI and Motility Disorders, Chapel Hill, North Carolina, United States

Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia in an Elderly Population

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2011-08-17
Last Posted Date
2011-08-17
Lead Sponsor
Banner Health
Target Recruit Count
20
Registration Number
NCT01418651
Locations
🇺🇸

Banner Sun Health Research Institute, Sun City, Arizona, United States

Study Evaluated the Effectiveness of Milnacipran to Reduce Pain Levels in Individuals With Chronic Migraine

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-07-13
Last Posted Date
2022-08-12
Lead Sponsor
Timothy Smith
Target Recruit Count
37
Registration Number
NCT01393522
Locations
🇺🇸

Headache Wellness Center, Greensboro, North Carolina, United States

🇺🇸

Mercy Health Research, Saint Louis, Missouri, United States

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