Overview
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180) In the US, methoxyflurane is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness.
Background
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180) In the US, methoxyflurane is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness.
Indication
作为全身麻醉药应用。
Associated Conditions
- Severe Pain
- Moderate Pain
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/06/12 | Phase 3 | Not yet recruiting | |||
2024/12/27 | Phase 1 | Recruiting | St. Paul's Hospital, Canada | ||
2024/04/30 | Phase 4 | Not yet recruiting | |||
2023/03/13 | Phase 4 | ENROLLING_BY_INVITATION | |||
2021/11/30 | Phase 3 | Completed | Oslo University Hospital | ||
2020/11/06 | Phase 3 | Completed | Hospital Authority, Hong Kong | ||
2020/07/17 | Phase 3 | Recruiting | Collegium Medicum w Bydgoszczy | ||
2020/03/03 | Not Applicable | Withdrawn | |||
2020/02/27 | Phase 4 | Completed | |||
2019/07/23 | Phase 4 | Completed | Dean Elterman |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| PENTHROX INHALATION LIQUID 99.9% | SIN14854P | INHALANT | 99.9% | 9/21/2015 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| PENTHROX INHALATION LIQUID 99.9% | N/A | N/A | N/A | 10/20/2018 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| OPHTH. LABS METHOXYFLURANE 3mL inhalation | 23287 | Medicine | A | 10/14/1991 | |
| Penthrox | 311927 | Medicine | A | 11/27/2018 | |
| PENTHROX methoxyflurane inhalation bottle | 43144 | Medicine | A | 1/18/1993 |