Methoxyflurane

Generic Name
Methoxyflurane
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C3H4Cl2F2O
CAS Number
76-38-0
Unique Ingredient Identifier
30905R8O7B
Background

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations ...

Indication

作为全身麻醉药应用。

Associated Conditions
Severe Pain, Moderate Pain
Associated Therapies
-

Methoxyflurane vs Standard Analgesic Treatment for Trauma Pain in Spanish Emergency Units

First Posted Date
2017-08-22
Last Posted Date
2018-08-20
Lead Sponsor
Mundipharma Pharmaceuticals S.L.
Target Recruit Count
310
Registration Number
NCT03256903
Locations
🇪🇸

Hospital del Bierzo, Ponferrada, León, Spain

🇪🇸

Hospital Virgen del Rocío, Sevilla, Spain

🇪🇸

Complejo Asistencial de Zamora, Zamora, Spain

and more 11 locations

Methoxyflurane Analgesia for Paediatric Injuries

First Posted Date
2017-07-12
Last Posted Date
2021-09-01
Lead Sponsor
Medical Developments International Limited
Target Recruit Count
222
Registration Number
NCT03215056
Locations
🇬🇧

Royal Devon and Exeter Hospital (Wonford), Exeter, Devon, United Kingdom

🇬🇧

Royal Alexandra Children's Hospital, Brighton, East Sussex, United Kingdom

🇬🇧

Leicester Royal Infirmary, Leicester, United Kingdom

and more 8 locations

Trial of Methoxyflurane With Periprostatic Local Anaesthesia to Reduce the Discomfort of TRUS B

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-11-13
Last Posted Date
2020-05-11
Lead Sponsor
University of Sydney
Target Recruit Count
420
Registration Number
NCT02604225
Locations
🇦🇺

Australian Clinical Trials, Wahroonga, New South Wales, Australia

🇦🇺

Concord Hospital, Concord, New South Wales, Australia

🇦🇺

Westmead Hospital, Westmead, Australia

and more 4 locations

Efficacy and Safety of Methoxyflurane (Penthrox) for the Treatment of Acute Pain in Minor Trauma

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-08-19
Last Posted Date
2012-10-31
Lead Sponsor
Medical Developments International Limited
Target Recruit Count
300
Registration Number
NCT01420159
Locations
🇬🇧

Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom

🇬🇧

James Cook University Hospital, Middlesbrough, United Kingdom

🇬🇧

Barnsley District General Hospital, Barnsley, United Kingdom

and more 3 locations

Safety and Efficacy of Methoxyflurane for Treatment of Incident Pain

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-09-05
Last Posted Date
2010-01-28
Lead Sponsor
Medical Developments International Limited
Target Recruit Count
110
Registration Number
NCT00524927
Locations
🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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