Methoxyflurane

Generic Name
Methoxyflurane
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C3H4Cl2F2O
CAS Number
76-38-0
Unique Ingredient Identifier
30905R8O7B
Background

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations ...

Indication

作为全身麻醉药应用。

Associated Conditions
Severe Pain, Moderate Pain
Associated Therapies
-

Prehospital Analgesia in Adults Using Inhaled Methoxyflurane Study

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-30
Last Posted Date
2024-07-19
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
1800
Registration Number
NCT06392087

Prehospital Inhaled Methoxyflurane Non-Clinical Occupational Exposure Study

Phase 4
Conditions
Interventions
First Posted Date
2023-03-13
Last Posted Date
2024-07-19
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
30
Registration Number
NCT05766397
Locations
🇨🇦

Dr Michael A Austin, Ottawa, Ontario, Canada

A Comparison of Three Regimens of Acute Pain Management: Methoxyflurane; Intranasal Fentanyl; Intravenous Morphine

First Posted Date
2021-11-30
Last Posted Date
2023-11-14
Lead Sponsor
Oslo University Hospital
Target Recruit Count
338
Registration Number
NCT05137184
Locations
🇳🇴

Sykehuset Innlandet, Gjøvik, Norway

A Pilot Study on the Use of Methoxyflurane (Penthrox®) for Pain Control in the Emergency Department

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-11-06
Last Posted Date
2020-12-08
Lead Sponsor
Hospital Authority, Hong Kong
Target Recruit Count
40
Registration Number
NCT04618497
Locations
🇭🇰

Hospital Authority, Hong Kong, Hong Kong

Low Dose Methoxyflurane and Out-Patient Aesthetic Surgery and Facial Filler

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2020-03-03
Last Posted Date
2023-05-06
Lead Sponsor
Verso Surgery Centre
Registration Number
NCT04292808
Locations
🇨🇦

Verso Surgery Centre, Oakville, Ontario, Canada

Prehospital Analgesia in Adults Using Inhaled Methoxyflurane : A Feasibility Study

Phase 4
Completed
Conditions
Interventions
First Posted Date
2020-02-27
Last Posted Date
2023-02-28
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
97
Registration Number
NCT04287803
Locations
🇨🇦

Dr Michael A Austin, Ottawa, Ontario, Canada

Penthrox in Rezūm BPH

Phase 4
Completed
Conditions
Interventions
First Posted Date
2019-07-23
Last Posted Date
2022-01-24
Lead Sponsor
Dean Elterman
Target Recruit Count
10
Registration Number
NCT04029012
Locations
🇨🇦

Can-Am HIFU Inc, Toronto, Ontario, Canada

Use of Methoxyflurane (Penthrox) as an Antalgic in Hospital Trauma

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2019-04-25
Last Posted Date
2021-05-06
Lead Sponsor
University Hospital, Tours
Target Recruit Count
34
Registration Number
NCT03927729
Locations
🇫🇷

Emergency Medical Service, University Hospital, Tours, Tours, France

MethOxyflUraNe at moderaTe High AltItudes for PAIN Management

Phase 4
Conditions
Interventions
First Posted Date
2019-02-21
Last Posted Date
2019-02-21
Lead Sponsor
University of Cape Town
Target Recruit Count
24
Registration Number
NCT03849027
Locations
🇿🇦

University of Cape Town Department of Anaesthesia & Perioperative Medicine, Cape Town, Western Cape, South Africa

Efficacy and Safety of Penthrox® Combined With a Standard Analgesia (SoC) in Adult Patients Admitted to the Emergency Department With Moderate to Severe Pain Associated With Trauma

Phase 4
Completed
Conditions
Interventions
First Posted Date
2019-01-10
Last Posted Date
2019-01-10
Lead Sponsor
Mundipharma SAS
Target Recruit Count
360
Registration Number
NCT03798899
Locations
🇫🇷

Hôpital Edouard Herriot, Lyon, France

🇫🇷

GH Carnelle Porte de l'Oise, Beaumont-sur-Oise, France

🇫🇷

CH Annecy Genevois, Annecy, France

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