Calcium gluconate
- Generic Name
- Calcium gluconate
- Drug Type
- Small Molecule
- Chemical Formula
- C12H22CaO14
- CAS Number
- 299-28-5
- Unique Ingredient Identifier
- SQE6VB453K
- Background
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate for intravenous use only. Each mL contains: Calcium gluconate 94 mg; calcium saccharate (tetrahydrate) 4.5 mg; water for injection q.s. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium gluconate.
Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate.
- Indication
Oral calcium salts are used as dietary supplemental therapy for person who may not get enough calcium in their regular diet. Calcium gluconate is used as a cardioprotective agent in high blood potassium. Calcium gluconate is the antidote for magnesium sulfate toxicity.
- Associated Conditions
- Bone and tooth decay, Bone and tooth growth, Calcium Deficiency, Hypocalcemia, Nutritional Rickets, Osteomalacia, Osteoporosis, Otospongiosis, Postmenopausal Osteoporosis, Vitamin D Insufficiency, Vitamin D Resistant Rickets
Calcium Administration in Life-saving Management During Massive Hemorrhage
- Conditions
- TraumaHypocalcemiaMassive Hemorrhage
- Interventions
- First Posted Date
- 2025-02-11
- Last Posted Date
- 2025-02-11
- Lead Sponsor
- London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
- Target Recruit Count
- 81
- Registration Number
- NCT06820645
Comparative Study Between Calcium Gluconate With Diosmin, Cabergoline and Cabergoline With Diosmin
- Conditions
- Ovarian Hyperstimulation Syndrome
- Interventions
- First Posted Date
- 2024-03-27
- Last Posted Date
- 2025-01-07
- Lead Sponsor
- Minia University
- Target Recruit Count
- 180
- Registration Number
- NCT06333691
- Locations
- 🇪🇬
Minia University, Faculty of Pharmacy, Minya, Egypt
Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
- Conditions
- Postpartum HemorrhagePregnancy RelatedHypocalcemiaParturition Complication
- Interventions
- First Posted Date
- 2023-08-03
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 34
- Registration Number
- NCT05973747
- Locations
- 🇺🇸
Lucile Packard Children's Hospital, Stanford, California, United States
CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
- Conditions
- TraumaHemorrhage
- Interventions
- First Posted Date
- 2023-07-24
- Last Posted Date
- 2025-01-10
- Lead Sponsor
- Jason Sperry
- Target Recruit Count
- 1050
- Registration Number
- NCT05958342
- Locations
- 🇺🇸
Allegheny Health Network, Pittsburgh, Pennsylvania, United States
🇺🇸University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Empiric Calcium in Massive Transfusion
- Conditions
- HemorrhageShock, HemorrhagicTraumaHypocalcemia
- Interventions
- First Posted Date
- 2023-07-20
- Last Posted Date
- 2024-04-08
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 30
- Registration Number
- NCT05953376
Endoscopic Assisted Calcium Electroporation in Esophageal Cancer
- First Posted Date
- 2021-07-12
- Last Posted Date
- 2022-10-26
- Lead Sponsor
- Michael Patrick Achiam
- Target Recruit Count
- 10
- Registration Number
- NCT04958044
- Locations
- 🇩🇰
Rigshospitalet, Copenhagen, Denmark
Prophylactic Infusion of Calcium Gluconate Reducing the Rate of Hypocalcaemia After Total Thyroidectomy
- First Posted Date
- 2020-07-29
- Last Posted Date
- 2020-07-31
- Lead Sponsor
- University of Malaya
- Target Recruit Count
- 50
- Registration Number
- NCT04491357
- Locations
- 🇲🇾
University Malaya Medical Centre, Kuala Lumpur, Malaysia
Cabergoline Versus Calcium Infusion in Ovarian Hyperstimulation Syndrome Prevention
- Conditions
- Ovarian Hyperstimulation
- Interventions
- First Posted Date
- 2018-03-22
- Last Posted Date
- 2018-03-29
- Lead Sponsor
- Benha University
- Target Recruit Count
- 230
- Registration Number
- NCT03473613
- Locations
- 🇪🇬
Ashraf nassif Elmantwe, Cairo, Elqalopia, Egypt
Cabergoline Versus Calcium Gluconate Infusion in the Prevention of Ovarian Hyperstimulation Syndrome
- First Posted Date
- 2016-08-23
- Last Posted Date
- 2018-12-27
- Lead Sponsor
- Aljazeera Hospital
- Target Recruit Count
- 170
- Registration Number
- NCT02875587
- Locations
- 🇪🇬
Aljazeera hospital, Giza, Egypt
🇪🇬Riyadh Fertility and Reproductive Health center, Giza, Egypt
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
- Conditions
- Chemotherapeutic Agent ToxicityColorectal CancerNeuropathyNeurotoxicity
- Interventions
- First Posted Date
- 2010-04-07
- Last Posted Date
- 2022-11-03
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 362
- Registration Number
- NCT01099449
- Locations
- 🇺🇸
Piedmont Hospital, Atlanta, Georgia, United States
🇺🇸Northside Hospital Cancer Center, Atlanta, Georgia, United States
🇺🇸Mason District Hospital, Havana, Illinois, United States
Drug Development Updates
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