Digoxin
- Generic Name
- Digoxin
- Brand Names
- Digox, Lanoxin
- Drug Type
- Small Molecule
- Chemical Formula
- C41H64O14
- CAS Number
- 20830-75-5
- Unique Ingredient Identifier
- 73K4184T59
- Background
Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954.
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- Indication
Digoxin is indicated in the following conditions: 1) For the treatment of mild to moderate heart failure in adult patients. 2) To increase myocardial contraction in children diagnosed with heart failure. 3) To maintain control ventricular rate in adult patients diagnosed with chronic atrial fibrillation.
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- Associated Conditions
- Myocardial contractility, Ventricular Arrhythmia, Mild to moderate heart failure
- Associated Therapies
- -
Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin
- First Posted Date
- 2008-07-28
- Last Posted Date
- 2010-12-02
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 24
- Registration Number
- NCT00723424
- Locations
- 🇩🇪
Research Site, Berlin, Germany
An Interaction Study With Digoxin and AZD1305
- First Posted Date
- 2008-07-10
- Last Posted Date
- 2010-12-03
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 18
- Registration Number
- NCT00712465
- Locations
- 🇸🇪
Research Site, Göteborg, Sweden
Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast Cancer
- First Posted Date
- 2008-04-02
- Last Posted Date
- 2017-11-17
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 17
- Registration Number
- NCT00650910
- Locations
- 🇰🇷
GSK Investigational Site, Seoul, Korea, Republic of
Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia
- First Posted Date
- 2006-10-20
- Last Posted Date
- 2017-12-13
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 72
- Registration Number
- NCT00390546
- Locations
- 🇨🇦
Hospital for Sick Kids, Toronto, Ontario, Canada
🇺🇸University of Southern California - Children's Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸The Children's Mercy Hospital, Kansas City, Missouri, United States
Pharmacokinetic and Pharmacodynamic Interaction Study of Digoxin and Hawthorn
- Conditions
- First Posted Date
- 2000-10-05
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Registration Number
- NCT00006330
- Locations
- 🇺🇸
Univ. of Michigan Medical Center, Ann Arbor, Michigan, United States
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)
- Conditions
Drug Development Updates
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