Silodosin
- Generic Name
- Silodosin
- Brand Names
- Rapaflo, Silodyx, Urorec, Silodosin Recordati
- Drug Type
- Small Molecule
- Chemical Formula
- C25H32F3N3O4
- CAS Number
- 160970-54-7
- Unique Ingredient Identifier
- CUZ39LUY82
- Background
Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the α subtype accounts for approximately 75% of α1-adrenoceptors in the prostate.
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- Indication
Silodosin is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH). It is not indicated for the treatment of hypertension.
- Associated Conditions
- Benign Prostatic Hyperplasia (BPH)
- Associated Therapies
- -
Silodosin in Management of Lower Ureteral Stones
- First Posted Date
- 2024-04-24
- Last Posted Date
- 2024-04-24
- Lead Sponsor
- Syrian Private University
- Target Recruit Count
- 100
- Registration Number
- NCT06381206
- Locations
- 🇸🇾
Damascus university, Damascus, Syrian Arab Republic
The Changes of Urine Growth Factors Level
- First Posted Date
- 2024-02-28
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- En Chu Kong Hospital
- Target Recruit Count
- 74
- Registration Number
- NCT06282731
- Locations
- 🇨🇳
En Chu Kong Hospital, New Taipei City, Taiwan
Silodosin vs Placebo in the Treatment of Female LUTS
- Conditions
- Interventions
- First Posted Date
- 2023-11-02
- Last Posted Date
- 2023-11-02
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 278
- Registration Number
- NCT06114979
Double J Stenting and Sildosin After URSL for Lower Ureteric Stones
- Conditions
- Interventions
- First Posted Date
- 2023-04-21
- Last Posted Date
- 2023-04-24
- Lead Sponsor
- Benha University
- Target Recruit Count
- 70
- Registration Number
- NCT05823662
- Locations
- 🇪🇬
Benha University Hospitals, Benha, Egypt
COMPARISON OF SILODOSIN AND TAMSULOSIN IN MEDICAL EXPULSIVE THERAPY OF DISTAL URETERIC CALCULI
- Conditions
- Interventions
- First Posted Date
- 2023-03-30
- Last Posted Date
- 2023-03-30
- Lead Sponsor
- Armed Forces Institute of Urology, Rawalpindi
- Target Recruit Count
- 142
- Registration Number
- NCT05790902
- Locations
- 🇵🇰
AFIU Rawalpindi, Rawalpindi, Punjab, Pakistan
Silodosin, Tadalafil Alone vs. Silodosin Plus Tadalafil as MET for Lower Ureteric Stones
- Conditions
- Interventions
- First Posted Date
- 2023-03-29
- Last Posted Date
- 2023-03-31
- Lead Sponsor
- Benha University
- Target Recruit Count
- 168
- Registration Number
- NCT05789732
- Locations
- 🇪🇬
Benha University Hospitals, Benha, Egypt
Silodosin vs Tamsulosin as MET
- First Posted Date
- 2022-10-06
- Last Posted Date
- 2022-10-06
- Lead Sponsor
- Princess Margaret Hospital, Hong Kong
- Target Recruit Count
- 80
- Registration Number
- NCT05570084
- Locations
- 🇭🇰
Hong Kong, Hong Kong, Hong Kong
Efficacy of Silodosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)
- First Posted Date
- 2019-09-27
- Last Posted Date
- 2019-09-27
- Target Recruit Count
- 141
- Registration Number
- NCT04107896
- Locations
- 🇧🇩
Maidul islam, Dhaka, Bangladesh
Safety and Efficacy of Silodosin in the Treatment of Premature Ejaculation
- First Posted Date
- 2015-10-21
- Last Posted Date
- 2016-01-05
- Target Recruit Count
- 40
- Registration Number
- NCT02581826
- Locations
- 🇨🇳
Cheng-Hsing Hsieh, Taipei, Xindian, Taiwan
Silodosin Versus Tamsulosin for Treatment of Ureteral Stones
- Conditions
- Interventions
- First Posted Date
- 2015-02-24
- Last Posted Date
- 2020-06-23
- Lead Sponsor
- Albert Einstein Healthcare Network
- Target Recruit Count
- 1
- Registration Number
- NCT02369744
- Locations
- 🇺🇸
Einstein Medical Center Philadelphia, Philadelphia, Pennsylvania, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.