Chloral hydrate

Generic Name
Chloral hydrate
Brand Names
Nortec
Drug Type
Small Molecule
Chemical Formula
C2H3Cl3O2
CAS Number
302-17-0
Unique Ingredient Identifier
418M5916WG
Background

A hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as an anti-anxiety medication.

Indication

Mainly used as a hypnotic in the treatment of insomnia; however, it is only effective as a hypnotic for short-term use. May be used as a routine sedative preoperatively to decrease anxiety and cause sedation and/or sleep with respiration depression or cough reflex.

Associated Conditions
Alcohol Withdrawal Syndrome, Opioid Withdrawal (Disorder), Postoperative pain, Barbiturate withdrawal
Associated Therapies
Sedative therapy

Chloral Hydrate to Perform Auditory Brainstem Response (ABR)

First Posted Date
2009-07-30
Last Posted Date
2009-07-31
Lead Sponsor
Pontificia Universidade Catolica de Sao Paulo
Target Recruit Count
41
Registration Number
NCT00949780
Locations
🇧🇷

Derdic-Pucsp, São Paulo, Brazil

🇧🇷

Mariana Lopes Favero, São Paulo, Brazil

Dexmedetomidine Versus Chloral Hydrate for Pediatric Sedation During EEG

First Posted Date
2007-04-23
Last Posted Date
2016-11-03
Lead Sponsor
Wesley Medical Center
Registration Number
NCT00464451
Locations
🇺🇸

Pediatric Sedation Unit, Wesley Medical Center, Wichita, Kansas, United States

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